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CAS 1229194-11-9
:Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, 4-methylbenzenesulfonate, hydrate (1:1:1)
Description:
Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, 4-methylbenzenesulfonate, hydrate (1:1:1) is a complex organic compound characterized by its multi-functional structure, which includes an ethanediamide backbone and various substituents that contribute to its biological activity. The presence of a chloro group and a pyridine ring suggests potential interactions with biological targets, making it of interest in medicinal chemistry. The compound also features a thiazole moiety, which is often associated with pharmacological properties. The sulfonate group enhances its solubility in aqueous environments, which is beneficial for biological applications. As a hydrate, it contains water molecules that can influence its stability and solubility. Overall, this compound's intricate structure and functional groups indicate potential utility in drug development, particularly in targeting specific biological pathways or receptors. Further studies would be necessary to elucidate its precise mechanisms of action and therapeutic potential.
Formula:C24H30ClN7O4S·C7H8O3S·H2O
InChI:InChI=1S/C24H30ClN7O4S.C7H8O3S.H2O/c1-31(2)24(36)13-4-6-15(27-20(33)21(34)30-19-7-5-14(25)11-26-19)17(10-13)28-22(35)23-29-16-8-9-32(3)12-18(16)37-23;1-6-2-4-7(5-3-6)11(8,9)10;/h5,7,11,13,15,17H,4,6,8-10,12H2,1-3H3,(H,27,33)(H,28,35)(H,26,30,34);2-5H,1H3,(H,8,9,10);1H2/t13-,15-,17+;;/m0../s1
InChI key:InChIKey=PSMMNJNZVZZNOI-SJILXJHISA-N
SMILES:N(C(=O)C1=NC2=C(S1)CN(C)CC2)[C@H]3[C@@H](NC(C(NC4=CC=C(Cl)C=N4)=O)=O)CC[C@H](C(N(C)C)=O)C3.S(=O)(=O)(O)C1=CC=C(C)C=C1.O
Synonyms:- Edoxaban Tosylate Monohydrate
- Edoxaban tosylate hydrate
- Edoxaban4-methylbenzenesulfonate, hydrate (1:1:1)
- Ethanediamide, N<sup>1</sup>-(5-chloro-2-pyridinyl)-N<sup>2</sup>-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, 4-methylbenzenesulfonate, hydrate (1:1:1)
- N-(5-Chloropyridin-2-yl)-N′-((1S,2R,4S)-4-[(dimethyl amino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl)ethanediamide p-toluenesulfonate monohydrate
- N-(5-Chloropyridin-2-yl)-N′-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide mono(p-toluenesulfonate) monohydrate
- Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, 4-methylbenzenesulfonate, hydrate (1:1:1)
- Edoxaban tosylate monohydrate(for Edoxaban)
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Found 8 products.
Edoxaban Tosylate
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C24H30ClN7O4S·C7H8O3S·H2OColor and Shape:White Off-White PowderMolecular weight:547.17685Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, 4-methylbenzenesulfonate, hydrate (1:1:1)
CAS:Formula:C31H40ClN7O8S2Purity:%Color and Shape:SolidMolecular weight:738.2744Edoxaban Tosylate Monohydrate
CAS:Edoxaban Tosylate MonohydrateFormula:C31H40ClN7O8S2Purity:≥98%Molecular weight:738.27N1-(5-Chloropyridin-2-Yl)-N2-((1S,2R,4S)-4-(Dimethylcarbamoyl)-2-(5-Methyl-4,5,6,7-Tetrahydrothiazolo[5,4-C]Pyridine-2-Carboxamido)Cyclohexyl)Oxalamide 4-Methylbenzenesulfonate Hydrate
CAS:N1-(5-Chloropyridin-2-Yl)-N2-((1S,2R,4S)-4-(Dimethylcarbamoyl)-2-(5-Methyl-4,5,6,7-Tetrahydrothiazolo[5,4-C]Pyridine-2-Carboxamido)Cyclohexyl)Oxalamide 4-Methylbenzenesulfonate HydrateFormula:C31H40ClN7O8S2Purity:≥98%Molecular weight:738.27Edoxaban Tosylate Monohydrate
CAS:Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.Formula:C31H40ClN7O8S2Purity:99.86% - 99.91%Color and Shape:SolidMolecular weight:738.27Edoxaban Tosylate Monohydrate
CAS:Applications Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor.
References Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010)Formula:C31H38ClN7O7S2•xH2OColor and Shape:NeatMolecular weight:720.26Edoxaban tosylate hydrate
CAS:Edoxaban tosylate hydrate is an anticoagulant that inhibits the activity of thrombin and factor Xa. It has a long half-life and does not undergo significant first-pass metabolism in the liver. Edoxaban tosylate hydrate is used for the prevention of stroke in patients with atrial fibrillation. It can be administered orally or by intravenous infusion, and its effect is monitored by measuring levels of the natriuretic peptide NT-proBNP. Edoxaban tosylate hydrate has a low potential for drug interactions, which may be due to its low protein binding affinity (less than 10%). This drug also inhibits P-glycoprotein, which may lead to bleeding complications.
Formula:C24H30ClN7O4S·C7H8O3S·H2OPurity:Min. 95%Molecular weight:738.28 g/mol
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