CAS 1233515-93-9
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Remogliflozin etabonate-d7
CAS:Remogliflozin etabonate-d7 (GSK189075-d7) is a deuterium-labeled form of Remogliflozin etabonate. Remogliflozin etabonate (GSK189075), an orally active, selective, and low-affinity sodium-glucose co-transporter (SGLT2) inhibitor, exhibits Ki values of 1.95 μM for hSGLT2, 43.1 μM for rSGLT2, 2.14 μM for hSGLT1, and 8.57 μM for rSGLT1. As a benzylpyrazole glucoside-based prodrug, it is metabolized in vivo to its active form, Remogliflozin, and demonstrates antidiabetic efficacy in rodent models.Formula:C26H38N2O9Molecular weight:529.64
