CAS 123748-68-5: escin Ia
Description:Escin Ia, also known as aescin or escin, is a triterpenoid saponin derived from the seeds of the horse chestnut tree (Aesculus hippocastanum). It is characterized by its complex structure, which includes a steroid-like backbone and sugar moieties. Escin Ia exhibits a range of biological activities, including anti-inflammatory, antioxidant, and venotonic properties, making it of interest in both pharmacological and cosmetic applications. It is often used in formulations aimed at improving venous circulation and reducing edema. The substance is soluble in water and organic solvents, which enhances its versatility in various formulations. Additionally, escin Ia has been studied for its potential therapeutic effects in conditions such as chronic venous insufficiency and hemorrhoids. Safety profiles indicate that it is generally well-tolerated, although some individuals may experience mild gastrointestinal disturbances. Overall, escin Ia is a significant compound in herbal medicine and pharmacology, valued for its beneficial effects on vascular health.
Formula:C55H86O24
InChI:InChI=1/C55H86O24/c1-10-23(2)46(71)79-43-44(72-24(3)60)55(22-59)26(17-50(43,4)5)25-11-12-30-51(6)15-14-32(52(7,21-58)29(51)13-16-53(30,8)54(25,9)18-31(55)61)75-49-41(77-48-38(67)36(65)34(63)28(20-57)74-48)39(68)40(42(78-49)45(69)70)76-47-37(66)35(64)33(62)27(19-56)73-47/h10-11,26-44,47-49,56-59,61-68H,12-22H2,1-9H3,(H,69,70)/b23-10+/t26-,27+,28+,29+,30+,31+,32-,33+,34+,35-,36-,37+,38+,39-,40-,41+,42-,43-,44-,47-,48-,49+,51-,52+,53+,54+,55-/m0/s1
- Synonyms:
- Aescin IA
- Aescin Ia(Sh)
- (3β,16α,21β,22α)-22-(acetyloxy)-16,24,28-trihydroxy-21-{[(2E)-2-methylbut-2-enoyl]oxy}olean-12-en-3-yl β-D-glucopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->4)]-β-D-glucopyranosiduronic acid