CAS 123748-68-5

escin Ia

Description:

Escin Ia, also known as aescin or escin, is a triterpenoid saponin derived from the seeds of the horse chestnut tree (Aesculus hippocastanum). It is characterized by its complex structure, which includes a steroid-like backbone and sugar moieties. Escin Ia exhibits a range of biological activities, including anti-inflammatory, antioxidant, and venotonic properties, making it of interest in both pharmacological and cosmetic applications. It is often used in formulations aimed at improving venous circulation and reducing edema. The substance is soluble in water and organic solvents, which enhances its versatility in various formulations. Additionally, escin Ia has been studied for its potential therapeutic effects in conditions such as chronic venous insufficiency and hemorrhoids. Safety profiles indicate that it is generally well-tolerated, although some individuals may experience mild gastrointestinal disturbances. Overall, escin Ia is a significant compound in herbal medicine and pharmacology, valued for its beneficial effects on vascular health.

Formula: C₅₅H₈₆O₂₄

InChI: InChI=1/C55H86O24/c1-10-23(2)46(71)79-43-44(72-24(3)60)55(22-59)26(17-50(43,4)5)25-11-12-30-51(6)15-14-32(52(7,21-58)29(51)13-16-53(30,8)54(25,9)18-31(55)61)75-49-41(77-48-38(67)36(65)34(63)28(20-57)74-48)39(68)40(42(78-49)45(69)70)76-47-37(66)35(64)33(62)27(19-56)73-47/h10-11,26-44,47-49,56-59,61-68H,12-22H2,1-9H3,(H,69,70)/b23-10+/t26-,27+,28+,29+,30+,31+,32-,33+,34+,35-,36-,37+,38+,39-,40-,41+,42-,43-,44-,47-,48-,49+,51-,52+,53+,54+,55-/m0/s1

Synonyms:

• Aescin IA
• Aescin Ia(Sh)
• (3β,16α,21β,22α)-22-(acetyloxy)-16,24,28-trihydroxy-21-{[(2E)-2-methylbut-2-enoyl]oxy}olean-12-en-3-yl β-D-glucopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->4)]-β-D-glucopyranosiduronic acid

AESCIN IA(SH)

CAS: 123748-68-5

Formula: C₅₅H₈₆O₂₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 1131.2569

Ref: IN-DA009BKG

Aescin IA

CAS: 123748-68-5

Formula: C₅₅H₈₆O₂₄

Purity: ≥ 99.0%

Color and Shape: White to off-white powder

Molecular weight: 1131.27

Ref: 7W-GY3202

Escin IA

CAS: 123748-68-5

Formula: C₅₅H₈₆O₂₄

Purity: 95%~99%

Molecular weight: 1131.27

Ref: BP-BP0556

Escin IA

CAS: 123748-68-5

Formula: C₅₅H₈₆O₂₄

Molecular weight: 1131.27

Ref: 4Z-I-083003

Escin IA

CAS: 123748-68-5

Escin IA (Escin IA;Aescin IA) is a triterpene saponin isolated from horse chestnut, which inhibits HIV-1 protease with IC50 values of 35 μM.

Formula: C₅₅H₈₆O₂₄

Purity: 98.97% - 99.81%

Color and Shape: Solid

Molecular weight: 1131.26

Ref: TM-T4S1383

Escin ia

CAS: 123748-68-5

Natural glycoside

Formula: C₅₅H₈₆O₂₄

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 1131.26

Ref: 5G-80445

Escin IA

CAS: 123748-68-5

Escin IA is a potent anti-inflammatory agent, which is a natural compound extracted from the seeds of the horse chestnut tree (Aesculus hippocastanum). This triterpenoid saponin operates by enhancing blood circulation and reducing capillary permeability through the stabilization of endothelial barriers. Additionally, it exhibits anti-edematous and venotonic activities by modifying vascular wall integrity and decreasing inflammatory mediators. Escin IA is widely utilized in biomedical research for its therapeutic potential in the management of chronic venous insufficiency, edema, and associated conditions. Its unique mechanism of action provides an intriguing area of study for scientists exploring vascular health, anti-inflammatory strategies, and natural therapeutic compounds. The ongoing research continues to validate its efficacy and explore broader applications in vascular and inflammatory disorders.

Purity: Min. 95%

Ref: 3D-FE145233

Escin Impurity A

CAS: 123748-68-5

Formula: C₅₅H₈₆O₂₄

Molecular weight: 1131.27

Ref: ST-EA-CP-E104001