CAS 1238673-32-9

Formula: C27H45N7O3

InChI: InChI=1S/C27H45N7O3/c1-31(2)15-16-36-17-18-37-25-20-23-22(19-24(25)35-5)26(28-21-7-11-33(4)12-8-21)30-27(29-23)34-10-6-9-32(3)13-14-34/h19-21H,6-18H2,1-5H3,(H,28,29,30)

InChI key: AULLUGALUBVBDD-UHFFFAOYSA-N

SMILES: CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)C)OC)OCCOCCN(C)C

UNC0321

CAS: 1238673-32-9

UNC0321

Formula: C₂₇H₄₅N₇O₃

Purity: ≥98%

Molecular weight: 515.69

Ref: 54-BUP05263

UNC0321

CAS: 1238673-32-9

Formula: C₂₇H₄₅N₇O₃

Purity: 99.80%

Molecular weight: 515.6913

Ref: IN-DA009CFD

UNC0321

CAS: 1238673-32-9

7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine

Formula: C₂₇H₄₅N₇O₃

Purity: 98%

Molecular weight: 515.69

Ref: IN-DG630040

UNC0321

Controlled Product

CAS: 1238673-32-9

UNC0321 is a methyltransferase inhibitor that binds to the active site of histone proteins. It has been shown to inhibit the methylation of lysine residues and prevent the formation of heterochromatin. UNC0321 is currently being investigated as an anti-infective agent for drug-resistant bacteria, such as Methicillin-resistant Staphylococcus aureus (MRSA), Pseudomonas aeruginosa, and Mycobacterium tuberculosis. The chemical structure of UNC0321 was designed by modifying a known inhibitor of p21 protein. This modification prevents the binding of the enzyme to the substrate, thus inhibiting transcriptional regulation in cells. UNC0321 has also been shown to have cytotoxic effects on liver cells due to its ability to suppress p21 protein levels and inhibit cell growth at low doses.

Formula: C₂₇H₄₅N₇O₃

Purity: Min. 95%

Molecular weight: 515.69 g/mol

Ref: 3D-NZB67332

UNC0321

CAS: 1238673-32-9

UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.

Formula: C₂₇H₄₅N₇O₃

Purity: 99.80%

Color and Shape: White Solid

Molecular weight: 515.6913

Ref: TM-T17204