CAS 123955-10-2

Almokalant

Description:

Almokalant, with the CAS number 123955-10-2, is a chemical compound that belongs to the class of antiarrhythmic agents. It is primarily characterized by its ability to block potassium channels, which plays a crucial role in the regulation of cardiac action potentials. This mechanism of action makes Almokalant effective in treating various types of cardiac arrhythmias by stabilizing the heart's rhythm. The compound is typically administered in a clinical setting, and its pharmacological profile includes properties such as a relatively short half-life and a specific affinity for certain ion channels. Almokalant's efficacy and safety profile have been the subject of research, particularly in the context of its potential side effects and interactions with other medications. As with many pharmacological agents, the therapeutic use of Almokalant requires careful consideration of dosage and patient-specific factors to optimize its benefits while minimizing risks. Overall, Almokalant represents a significant advancement in the field of cardiology, particularly for patients with arrhythmic conditions.

Formula: C₁₈H₂₈N₂O₃S

InChI: InChI=1S/C18H28N2O3S/c1-3-11-24(22)12-5-10-20(4-2)14-17(21)15-23-18-8-6-16(13-19)7-9-18/h6-9,17,21H,3-5,10-12,14-15H2,1-2H3

InChI key: InChIKey=ZMHOBBKJBYLXFR-UHFFFAOYSA-N

SMILES: O(CC(CN(CCCS(CCC)=O)CC)O)C1=CC=C(C#N)C=C1

Synonyms:

• (+-)-p-(3-(Ethyl(3-(propylsulfinyl)propyl)amino)-2-hydroxypropoxy)benzonitrile
• 4-(3-(Ethyl(3-(propylsulfinyl)propyl)amino)-2-hydroxypropoxy)benzonitrile
• Almokalant [INN]
• Almokalantum
• Almokalantum [INN-Latin]
• Benzonitrile, 4-(3-(ethyl(3-(propylsulfinyl)propyl)amino)-2-hydroxypropoxy)-
• H 234/09
• Unii-I9Ng89L275
• Almokalant

Almokalant

CAS: 123955-10-2

Formula: C₁₈H₂₈N₂O₃S

Molecular weight: 352.49

Ref: 4Z-A-261001

Almokalant

CAS: 123955-10-2

Almokalant is an investigational antiarrhythmic drug, which is a synthetic pharmaceutical compound. It is derived from the class of drugs known as selective potassium channel blockers. Almokalant's mode of action involves the blockade of hERG (human Ether-à-go-go-Related Gene) potassium channels. This blockade prolongs the cardiac action potential duration, which can be beneficial in stabilizing irregular heartbeats.

Formula: C₁₈H₂₈N₂O₃S

Purity: Min. 95%

Molecular weight: 352.5 g/mol

Ref: 3D-YEA95510

Almokalant

CAS: 123955-10-2

Formula: C₁₈H₂₈N₂O₃S

Molecular weight: 352.49

Ref: ST-EA-CP-A292000

Almokalant

CAS: 123955-10-2

Almokalant: Class III antiarrhythmic, K+ channel blocker, inhibits Ikr current.

Formula: C₁₈H₂₈N₂O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 352.49

Ref: TM-T14189