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CAS 1243243-89-1

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Wnt-C59 (C59)

Description:
Wnt-C59, also known by its CAS number 1243243-89-1, is a small molecule inhibitor that specifically targets the Wnt signaling pathway, which plays a crucial role in various biological processes, including cell proliferation, differentiation, and embryonic development. This compound is particularly noted for its ability to inhibit the activity of Porcupine, an enzyme involved in the palmitoylation of Wnt proteins, thereby preventing their secretion and subsequent signaling. Wnt-C59 has garnered interest in the field of cancer research, as aberrant Wnt signaling is often implicated in tumorigenesis. The compound is typically characterized by its moderate solubility in organic solvents and its stability under physiological conditions. In preclinical studies, Wnt-C59 has shown potential in reducing tumor growth in models of Wnt-dependent cancers, making it a candidate for further investigation in therapeutic applications. However, as with any investigational compound, its safety, efficacy, and pharmacokinetics require thorough evaluation through clinical trials before any potential clinical use.
Formula:C25H21N3O
InChI:InChI=1S/C25H21N3O/c1-18-15-22(12-14-27-18)20-6-4-19(5-7-20)16-25(29)28-24-10-8-21(9-11-24)23-3-2-13-26-17-23/h2-15,17H,16H2,1H3,(H,28,29)
InChI key:KHZOJCQBHJUJFY-UHFFFAOYSA-N
SMILES:CC1=NC=CC(=C1)C2=CC=C(C=C2)CC(=O)NC3=CC=C(C=C3)C4=CN=CC=C4
Synonyms:
  • Wnt-C59
  • WNT C59
  • 4-(2-Methyl-4-pyridinyl)-N-[4-(3-pyridinyl)phenyl]benzeneacetamide
  • 2-(4-(2-Methylpyridin-4-yl)phenyl)-N-(4-(pyridin-3-yl)phenyl)acetaMide
Found 10 products.