CAS 1243245-18-2

Formula: C24H25FN6O2

InChI: InChI=1S/C24H25FN6O2/c1-16-11-18(14-28-24(16)19-5-6-26-21(25)13-19)12-23(33)29-22-4-3-20(15-27-22)31-9-7-30(8-10-31)17(2)32/h3-6,11,13-15H,7-10,12H2,1-2H3,(H,27,29,33)

InChI key: AXXNRMISICMFNS-UHFFFAOYSA-N

SMILES: CC1=CC(=CN=C1C2=CC(=NC=C2)F)CC(=O)NC3=NC=C(C=C3)N4CCN(CC4)C(=O)C

GNF-6231

CAS: 1243245-18-2

GNF-6231

Formula: C₂₄H₂₅FN₆O₂

Purity: 99.5%

Molecular weight: 448.49

Ref: 54-BUP11510

GNF-6231

CAS: 1243245-18-2

Formula: C₂₄H₂₅FN₆O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 448.4927

Ref: IN-DA009CMZ

GNF-6231

CAS: 1243245-18-2

GNF-6231 is a small molecule that inhibits the transcriptional regulator β-catenin, which is involved in the Wnt pathway. GNF-6231 has been shown to inhibit colorectal carcinoma growth and metastasis, as well as induce cardiac and ventricular dysfunction in mice. It also inhibits hepatocellular carcinoma growth and metastasis in mice. The drug can be used to treat cancer by inhibiting the progression of cancer cells. This drug has been shown to be effective against monoclonal antibodies against β-catenin, including cetuximab, which is used to treat colorectal carcinoma.

Formula: C₂₄H₂₅FN₆O₂

Purity: Min. 95%

Molecular weight: 448.49 g/mol

Ref: 3D-TZB24518

GNF-6231

CAS: 1243245-18-2

GNF-6231 is a potent, selective, and orally bioavailable Porcupine inhibitor that blocks Wnt signaling.

Formula: C₂₄H₂₅FN₆O₂

Purity: 99.74% - >99.99%

Color and Shape: Solid

Molecular weight: 448.4927

Ref: TM-T11444