CAS 124436-59-5

Pirodavir

Description:

Pirodavir is an antiviral compound primarily investigated for its potential in treating viral infections, particularly those caused by rhinoviruses, which are responsible for the common cold. It belongs to the class of compounds known as nucleoside analogs, which mimic the structure of natural nucleosides and interfere with viral replication. Pirodavir exhibits a mechanism of action that involves inhibiting viral RNA synthesis, thereby preventing the virus from multiplying within host cells. The substance is characterized by its relatively low molecular weight and specific functional groups that contribute to its antiviral activity. In terms of solubility, Pirodavir is typically evaluated in various solvents to determine its bioavailability and pharmacokinetic properties. While it has shown promise in preclinical studies, further research is necessary to fully understand its efficacy, safety profile, and potential therapeutic applications in clinical settings. As with many antiviral agents, the development of resistance and the need for combination therapies are important considerations in its use.

Formula: C₂₁H₂₇N₃O₃

InChI: InChI=1/C21H27N3O3/c1-3-26-21(25)18-5-7-19(8-6-18)27-15-12-17-10-13-24(14-11-17)20-9-4-16(2)22-23-20/h4-9,17H,3,10-15H2,1-2H3

SMILES: CCOC(=O)c1ccc(cc1)OCCC1CCN(CC1)c1ccc(C)nn1

Synonyms:

• Pirodavir [USAN:INN:BAN]
• Benzoic acid, 4-(2-(1-(6-methyl-3-pyridazinyl)-4-piperidinyl)ethoxy)-, ethyl ester
• Ethyl p-(2-(1-(6-methyl-3-pyridazinyl)-4-piperidyl)ethoxy)benzoate
• Pirodavirum
• Pirodavirum [INN-Latin]
• R 77975
• Unii-Bml697718K
• Ethyl 4-{2-[1-(6-Methylpyridazin-3-Yl)Piperidin-4-Yl]Ethoxy}Benzoate

Benzoic acid, 4-[2-[1-(6-methyl-3-pyridazinyl)-4-piperidinyl]ethoxy]-, ethyl ester

CAS: 124436-59-5

Formula: C₂₁H₂₇N₃O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 369.4574

Ref: IN-DA000M0M

Ethyl 4-(2-(1-(6-Methylpyridazin-3-Yl)Piperidin-4-Yl)Ethoxy)Benzoate

CAS: 124436-59-5

Ethyl 4-(2-(1-(6-Methylpyridazin-3-Yl)Piperidin-4-Yl)Ethoxy)Benzoate

Purity: 98%

Molecular weight: 369.46g/mol

Ref: 54-OR1023345

Pirodavir

CAS: 124436-59-5

Pirodavir

Purity: ≥98%

Molecular weight: 369.46g/mol

Ref: 54-BUP12810

Pirodavir

CAS: 124436-59-5

Formula: C₂₁H₂₇N₃O₃

Purity: >95.0%(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 369.47

Ref: 3B-P2665

Pirodavir

CAS: 124436-59-5

Pirodavir (R77975) (R 77975), the prototype of broad-spectrum anti-picornavirus compounds, is a potent human rhinovirus (HRV) capsid-binding inhibitor.

Formula: C₂₁H₂₇N₃O₃

Purity: 98.43% - 99.47%

Color and Shape: Solid

Molecular weight: 369.46

Ref: TM-T1750

Benzoic acid, 4-[2-[1-(6-methyl-3-pyridazinyl)-4-piperidinyl]ethoxy]-, ethyl ester

CAS: 124436-59-5

Purity: ≥98%

Molecular weight: 369.4649963

Ref: 10-F861640

R 77975

Controlled Product

CAS: 124436-59-5

Applications R 77975 is used to modulate lipophilicity in human rhinovirus capsid binders. It also is used in order to identify potential ativiral agents.
References Morley, A. et al.: Bioorg. Med. Chem. Lett., 21, 6031 (2011); Tomkinson, N. et al.: Bioorg. Med. Chem. Lett., 22, 7494 (2012);

Formula: C₂₁H₂₇N₃O₃

Color and Shape: Neat

Molecular weight: 369.46

Ref: TR-R070125

Pirodavir

CAS: 124436-59-5

Pirodavir is a potent antiviral compound, which is a synthetic molecule developed through pharmaceutical research. It acts by targeting the rhinovirus, the most common viral infectious agent in humans, primarily responsible for the common cold. Pirodavir's mode of action involves binding to the viral capsid, thereby preventing the uncoating process essential for viral replication.

Formula: C₂₁H₂₇N₃O₃

Purity: Min. 95%

Molecular weight: 369.46 g/mol

Ref: 3D-ZEA43659