CAS 1245907-03-2

3-Pyridinecarbonitrile, 2-[(5-hydroxy-1,5-dimethylhexyl)amino]-4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-, hydrochloride (1:1)

Description:

3-Pyridinecarbonitrile, 2-[(5-hydroxy-1,5-dimethylhexyl)amino]-4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-, hydrochloride (1:1) is a complex organic compound characterized by its multi-functional structure, which includes a pyridine ring, a carbonitrile group, and various amino substituents. The presence of the hydroxyl group and multiple methyl groups contributes to its solubility and potential biological activity. As a hydrochloride salt, it is typically more stable and soluble in aqueous solutions, which is advantageous for pharmaceutical applications. This compound may exhibit specific pharmacological properties, potentially acting as a ligand or inhibitor in biological systems, although detailed biological activity data would be necessary for a comprehensive understanding. Its molecular structure suggests potential interactions with various biological targets, making it of interest in medicinal chemistry. Safety and handling precautions should be observed, as with all chemical substances, particularly in laboratory settings.

Formula: C₁₉H₂₉ClN₆O

InChI: InChI=1S/C19H28N6O.ClH/c1-12-9-16(22-17-10-14(3)24-25-17)23-18(15(12)11-20)21-13(2)7-6-8-19(4,5)26;/h9-10,13,26H,6-8H2,1-5H3,(H3,21,22,23,24,25);1H

InChI key: InChIKey=DXVATYHPJJPMIN-UHFFFAOYSA-N

SMILES: N(C(CCCC(C)(C)O)C)C1=C(C#N)C(C)=CC(NC2=NNC(C)=C2)=N1.Cl

Synonyms:

• 3-Pyridinecarbonitrile, 2-[(5-hydroxy-1,5-dimethylhexyl)amino]-4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-, hydrochloride (1:1)
• TC-A 2317-hydrochloride
• Reaxys ID: 20640556
• 2-[(5-Hydroxy-1,5-dimethylhexyl)amino]-4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-3-pyridinecarbonitrile hydrochloride
• permeability,oral,Inhibitor,selective,antitumor,inhibit,HCT-116,TC A 2317 hydrochloride,TCA 2317 hydrochloride,Aurora Kinase,proliferation,TC-A 2317
• TC-A-2317 HCl

TC-A2317 hydrochloride

CAS: 1245907-03-2

TC-A2317 hydrochloride is a selective nicotinic acetylcholine receptor (nAChR) agonist, which is synthesized through chemical methods. It acts by specifically targeting nAChRs, which are ionotropic receptors predominantly found in the central nervous system and peripheral nervous system. These receptors are ligand-gated ion channels that, upon activation by agonists like TC-A2317 hydrochloride, result in increased neuronal excitability and neurotransmitter release.

Formula: C₁₉H₂₈N₆O·HCl

Purity: Min. 95%

Molecular weight: 392.93 g/mol

Ref: 3D-VZB90703

TC-A 2317 hydrochloride

CAS: 1245907-03-2

TC-A 2317 HCl inhibits Aurora A kinase (Ki 1.2 nM) over Aurora B (Ki 101 nM), displaying antitumor effects.

Formula: C₁₉H₂₉ClN₆O

Purity: 98%

Color and Shape: Solid

Molecular weight: 392.93

Ref: TM-T23426