CAS 124750-99-8

Losartan Potassium

Description:

Losartan Potassium is an angiotensin II receptor antagonist primarily used in the treatment of hypertension and to protect the kidneys in patients with type 2 diabetes. It is a white to off-white crystalline powder that is soluble in water and exhibits a molecular formula of C22H22ClN6O. The compound works by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict, thereby promoting vasodilation and reducing blood pressure. Losartan Potassium is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing. It may also have additional benefits in heart failure and stroke prevention. Common side effects can include dizziness, fatigue, and gastrointestinal disturbances, while serious adverse effects may involve renal impairment or hyperkalemia. As with any medication, it is essential to use Losartan Potassium under medical supervision, considering potential interactions with other drugs and individual patient health profiles.

Formula: C₂₂H₂₃ClKN₆O

InChI: InChI=1/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12H,2-3,8,13-14H2,1H3,(H,25,26,27,28);/q-1;+1

InChI key: InChIKey=FDKIDFYIEWFERB-UHFFFAOYSA-N

SMILES: C(N1C(CCCC)=NC(Cl)=C1CO)C2=CC=C(C=C2)C3=C(C=CC=C3)C=4NN=NN4.[K]

Synonyms:

• 1H-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-, monopotassium salt
• 1H-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-, potassium salt (1:1)
• 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol monopotassium salt
• Amosar
• Aradois
• Cozaar
• Du Pont 753
• DuP 753
• Losacar
• Losar
• Losartan monopotassium salt
• Losartan potassium salt
• Losata
• Losatan potassium
• Losium
• Mk 954
• Nu-Lotan
• Potassium 5-(4′-((2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl)methyl)-[1,1′-biphenyl]-2-yl)tetrazol-1-ide
• Presartan 50
• Tancin
• Zaart
• potassium (2-butyl-4-chloro-1-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanolate
• potassium 5-(4'-{[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl}biphenyl-2-yl)tetrazol-1-ide
• MK-95
• thanolpotassium
• LOSARTANPOTASSIUM(SUBJECTTOPATENTFREE)
• 2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOLE-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-METHANOL, POTASSIUM SALT
• l-158086
• dupont753
• 2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOL-5YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-METHANOL
• LOSARTAN POTASSIUM
• mk-0954
• 1h-imidazole-5-methanol,2-butyl-4-chloro-1-((2’-(1h-tetrazol-5-yl)(1,1’-biphe
• 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-

Losartan Potassium

CAS: 124750-99-8

Formula: C₂₂H₂₂ClKN₆O

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 461.01

Ref: 3B-L0232

LOSARTAN POTASSIUM CRS

CAS: 124750-99-8

LOSARTAN POTASSIUM CRS

Formula: C₂₂H₂₂ClKN₆O

Color and Shape: Crystalline Powder. White. Powder.

Molecular weight: 461.001

Ref: 41-Y0001062

Losartan potassium

CAS: 124750-99-8

Losartan potassium

Formula: C₂₂H₂₂ClKN₆O

Purity: 99.9%

Color and Shape: White

Molecular weight: 460.11807

Ref: 47-867

Losartan Potassium

CAS: 124750-99-8

Compounds containing an unfused imidazole ring (whether

Formula: C₂₂H₂₂ClN₆OK

Color and Shape: White Off-White Crystalline Powder

Molecular weight: 460.11807

Ref: 45-1370462

1H-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, potassium salt (1:1)

CAS: 124750-99-8

Formula: C₂₂H₂₂ClKN₆O

Purity: 98%

Color and Shape: Solid

Molecular weight: 461.0010

Ref: IN-DA000MPS

Losartan potassium

CAS: 124750-99-8

Losartan potassium (DuP-753 potassium) , an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to the

Formula: C₂₂H₂₂ClKN₆O

Purity: 99.9% - >99.99%

Color and Shape: White To Off-White Crystalline Powder

Molecular weight: 461.01

Ref: TM-T0215

Losartan potassium salt

CAS: 124750-99-8

Formula: C₂₂H₂₃ClKN₆O

Molecular weight: 462.01

Ref: 7W-GP4595

Losartan potassium

CAS: 124750-99-8

Losartan potassium

Purity: ≥98%

Molecular weight: 461.01g/mol

Ref: 54-BUP18509

Losartan Potassium Salt

CAS: 124750-99-8

Formula: C₂₂H₂₂ClN₆O·K

Color and Shape: Off-White Solid

Molecular weight: 421.91 39.10

Ref: 4Z-L-111

Losartan Potassium

Controlled Product

CAS: 124750-99-8

Formula: C₂₂H₂₂ClN₆O·K

Color and Shape: Neat

Molecular weight: 461.00

Ref: 86-MM0168.03

Losartan potassium

Controlled Product

CAS: 124750-99-8

Formula: C₂₂H₂₂ClN₆O·K

Color and Shape: Neat

Molecular weight: 461.00

Ref: 04-C14648175

Losartan Potassium RS

CAS: 124750-99-8

Color and Shape: White Solid Crystalline Powder

Ref: 2K-1188500021

Losartan Potassium

CAS: 124750-99-8

Formula: C₂₂H₂₂ClN₆OK

Molecular weight: 421.91 : 39.10

Ref: ST-EA-CP-L25000

Losartan Potassium Salt

Controlled Product

CAS: 124750-99-8

Applications A nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.
References Chiu, T.A., et al.: J. Pharmacol. Exp. Ther., 252, 711 (1990), McIntyre, M., et al.: Pharmacol. Ther., 74, 181 (1997), Pitt, B., et al.: Lancet, 355, 1582 (2000);

Formula: C₂₂H₂₂ClN₆O·K

Color and Shape: White

Molecular weight: 461.00

Ref: TR-L470500

Losartan potassium

CAS: 124750-99-8

Non-peptide angiotensin AT1 receptor antagonist; anti-hypertensive

Formula: C₂₂H₂₂ClKN₆O

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 461 g/mol

Ref: 3D-FL24945

Losartan potassium - Bio-X ™

CAS: 124750-99-8

Losartan is an angiotensin receptor drug that is used to treat hypertension. It works by blocking the activity of angiotensin II binding to the AT1 receptor. As a result, this causes vascular smooth muscle relaxation and lowers blood pressure.

Formula: C₂₂H₂₂ClKN₆O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 461 g/mol

Ref: 3D-BL164642