CAS 124750-99-8
:Losartan Potassium
Description:
Losartan Potassium is an angiotensin II receptor antagonist primarily used in the treatment of hypertension and to protect the kidneys in patients with type 2 diabetes. It is a white to off-white crystalline powder that is soluble in water and exhibits a molecular formula of C22H22ClN6O. The compound works by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict, thereby promoting vasodilation and reducing blood pressure. Losartan Potassium is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing. It may also have additional benefits in heart failure and stroke prevention. Common side effects can include dizziness, fatigue, and gastrointestinal disturbances, while serious adverse effects may involve renal impairment or hyperkalemia. As with any medication, it is essential to use Losartan Potassium under medical supervision, considering potential interactions with other drugs and individual patient health profiles.
Formula:C22H23ClKN6O
InChI:InChI=1/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12H,2-3,8,13-14H2,1H3,(H,25,26,27,28);/q-1;+1
InChI key:InChIKey=FDKIDFYIEWFERB-UHFFFAOYSA-N
SMILES:C(N1C(CCCC)=NC(Cl)=C1CO)C2=CC=C(C=C2)C3=C(C=CC=C3)C=4NN=NN4.[K]
Synonyms:- 1H-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-, monopotassium salt
- 1H-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-, potassium salt (1:1)
- 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol monopotassium salt
- Amosar
- Aradois
- Cozaar
- Du Pont 753
- DuP 753
- Losacar
- Losar
- Losartan monopotassium salt
- Losartan potassium salt
- Losata
- Losatan potassium
- Losium
- Mk 954
- Nu-Lotan
- Potassium 5-(4′-((2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl)methyl)-[1,1′-biphenyl]-2-yl)tetrazol-1-ide
- Presartan 50
- Tancin
- Zaart
- potassium (2-butyl-4-chloro-1-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanolate
- potassium 5-(4'-{[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl}biphenyl-2-yl)tetrazol-1-ide
- MK-95
- thanolpotassium
- LOSARTANPOTASSIUM(SUBJECTTOPATENTFREE)
- 2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOLE-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-METHANOL, POTASSIUM SALT
- l-158086
- dupont753
- 2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOL-5YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-METHANOL
- LOSARTAN POTASSIUM
- mk-0954
- 1h-imidazole-5-methanol,2-butyl-4-chloro-1-((2’-(1h-tetrazol-5-yl)(1,1’-biphe
- 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-
- See more synonyms
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Found 18 products.
Losartan potassium
CAS:Losartan potassiumFormula:C22H22ClKN6OPurity:99.9%Color and Shape:WhiteMolecular weight:460.11807LOSARTAN POTASSIUM CRS
CAS:LOSARTAN POTASSIUM CRSFormula:C22H22ClKN6OColor and Shape:Crystalline Powder. White. Powder.Molecular weight:461.001Losartan Potassium
CAS:Compounds containing an unfused imidazole ring (whetherFormula:C22H22ClN6OKColor and Shape:White Off-White Crystalline PowderMolecular weight:460.11807Losartan potassium
CAS:Losartan potassiumFormula:C22H22ClKN6OPurity:≥98%Color and Shape:SolidMolecular weight:461.011H-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, potassium salt (1:1)
CAS:Formula:C22H22ClKN6OPurity:98%Color and Shape:SolidMolecular weight:461.0010Losartan potassium
CAS:Losartan potassium (DuP-753 potassium) , an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to theFormula:C22H22ClKN6OPurity:99.9% - >99.99%Color and Shape:White SolidMolecular weight:461.01Losartan Potassium Salt
CAS:Formula:C22H22ClN6O·KColor and Shape:Off-White SolidMolecular weight:421.91 39.10Losartan Potassium
CAS:Formula:C22H22ClKN6OPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:461.01Losartan Potassium
CAS:Controlled ProductFormula:C22H22ClN6O·KColor and Shape:NeatMolecular weight:461.00Losartan potassium
CAS:Controlled ProductFormula:C22H22ClN6O·KColor and Shape:NeatMolecular weight:461.00Losartan potassium
CAS:(1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol, potassium saltFormula:C22H22ClKN6OPurity:98%Molecular weight:461.0Losartan Potassium Salt
CAS:Controlled ProductApplications A nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.
References Chiu, T.A., et al.: J. Pharmacol. Exp. Ther., 252, 711 (1990), McIntyre, M., et al.: Pharmacol. Ther., 74, 181 (1997), Pitt, B., et al.: Lancet, 355, 1582 (2000);Formula:C22H22ClN6O·KColor and Shape:NeatMolecular weight:461.00Losartan potassium
CAS:Non-peptide angiotensin AT1 receptor antagonist; anti-hypertensiveFormula:C22H22ClKN6OPurity:Min. 95%Color and Shape:White PowderMolecular weight:461 g/molLosartan potassium - Bio-X ™
CAS:Losartan is an angiotensin receptor drug that is used to treat hypertension. It works by blocking the activity of angiotensin II binding to the AT1 receptor. As a result, this causes vascular smooth muscle relaxation and lowers blood pressure.Formula:C22H22ClKN6OPurity:Min. 95%Color and Shape:PowderMolecular weight:461 g/mol
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