CAS 124858-35-1
:Nadifloxacin
Description:
Nadifloxacin is a synthetic fluoroquinolone antibiotic primarily used in dermatological applications for the treatment of bacterial skin infections. It exhibits broad-spectrum antibacterial activity, particularly against Gram-positive bacteria, including strains resistant to other antibiotics. The compound functions by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription. Nadifloxacin is characterized by its lipophilicity, which enhances its penetration through the skin, making it effective for topical formulations. It is typically available in various forms, including creams and gels, and is known for its relatively low systemic absorption when applied topically. Additionally, Nadifloxacin has anti-inflammatory properties, which can aid in reducing redness and swelling associated with skin infections. Its safety profile is generally favorable, with minimal side effects reported, although local irritation may occur in some patients. Overall, Nadifloxacin represents a valuable option in the management of localized bacterial skin conditions.
Formula:C19H21FN2O4
InChI:InChI=1/C19H21FN2O4/c1-10-2-3-12-16-13(18(24)14(19(25)26)9-22(10)16)8-15(20)17(12)21-6-4-11(23)5-7-21/h8-11,23H,2-7H2,1H3,(H,25,26)
InChI key:InChIKey=JYJTVFIEFKZWCJ-UHFFFAOYSA-N
SMILES:O=C1C=2C3=C(C(=C(F)C2)N4CCC(O)CC4)CCC(C)N3C=C1C(O)=O
Synonyms:- (±)-9-Fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic Acid
- 124858-35-1
- 1H,5H-Benzo[ij]quinolizine-2-carboxylic acid, 9-fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-
- 9-Fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid
- Jinofloxacin
- Nadibact
- Nadixa
- Opc 7251
- Nadifloxacin
- Acuatim
- Nadiroxisan
- (+/-)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidino)-5-methyl-1-oxo-1h,5h-benzo[ij]quinolizine-2-carboxylic acid
- Nadiflo
- opc7251
- NDFX
- Acuati
- 1H,5H-Benzo[ij]quinolizine-2-carboxylic acid, 9-fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-(9CI)
- See more synonyms
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Found 12 products.
Nadifloxacin
CAS:Formula:C19H21FN2O4Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:360.39Nadifloxacin
CAS:Nadifloxacin (OPC7251) has been used in trials studying the treatment of Acne Vulgaris.Formula:C19H21FN2O4Purity:99.03% - 99.7%Color and Shape:Off-White Crystalline SolidMolecular weight:360.387-fluoro-8-(4-hydroxypiperidin-1-yl)-12-methyl-4-oxo-1-azatricyclo[7.3.1.0^{5,13}]trideca-2,5(13),6,8-tetraene-3-carboxylic acid
CAS:Formula:C19H21FN2O4Purity:98%Color and Shape:SolidMolecular weight:360.3794Nadifloxacin
CAS:<p>Applications Fluorinated quinolone antibacterial (topical).<br>References Kurokawa, I., et al.: J. Am. Acad. Dermatol., 25, 674 (1991),<br></p>Formula:C19H21FN2O4Color and Shape:White To Off-WhiteMolecular weight:360.38Nadifloxacin
CAS:<p>Nadifloxacin is a fluoroquinolone antibiotic with action on bacterial DNA gyrase to inhibit DNA synthesis and is used for treating acne vulgaris and bacterial skin infections.</p>Formula:C19H21FN2O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:360.38 g/mol
![7-fluoro-8-(4-hydroxypiperidin-1-yl)-12-methyl-4-oxo-1-azatricyclo[7.3.1.0^{5,13}]trideca-2,5(13),…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA000MTZ.jpg&w=3840&q=75)
