CAS 124858-35-1: Nadifloxacin
Description:Nadifloxacin is a synthetic fluoroquinolone antibiotic primarily used in dermatological applications for the treatment of bacterial skin infections. It exhibits broad-spectrum antibacterial activity, particularly against Gram-positive bacteria, including strains resistant to other antibiotics. The compound functions by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription. Nadifloxacin is characterized by its lipophilicity, which enhances its penetration through the skin, making it effective for topical formulations. It is typically available in various forms, including creams and gels, and is known for its relatively low systemic absorption when applied topically. Additionally, Nadifloxacin has anti-inflammatory properties, which can aid in reducing redness and swelling associated with skin infections. Its safety profile is generally favorable, with minimal side effects reported, although local irritation may occur in some patients. Overall, Nadifloxacin represents a valuable option in the management of localized bacterial skin conditions.
Formula:C19H21FN2O4
InChI:InChI=1S/C19H21FN2O4/c1-10-2-3-12-16-13(18(24)14(19(25)26)9-22(10)16)8-15(20)17(12)21-6-4-11(23)5-7-21/h8-11,23H,2-7H2,1H3,(H,25,26)
InChI key:InChIKey=JYJTVFIEFKZWCJ-UHFFFAOYSA-N
SMILES:O=C(O)C1=CN2C=3C(=CC(F)=C(C3CCC2C)N4CCC(O)CC4)C1=O
- Synonyms:
- (±)-9-Fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic Acid
- 124858-35-1
- 1H,5H-Benzo[ij]quinolizine-2-carboxylic acid, 9-fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-
- 9-Fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid
- Jinofloxacin
- Nadibact
- Nadixa
- Opc 7251
- Nadifloxacin
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