CAS 125-70-2
:Levomethorphan
Description:
Levomethorphan is an opioid analgesic and antitussive agent, primarily used for its cough-suppressing properties. It is a stereoisomer of methorphan, which means it has a specific three-dimensional arrangement of atoms that influences its pharmacological effects. As a white to off-white crystalline powder, levomethorphan is soluble in organic solvents but has limited solubility in water. Its mechanism of action involves binding to opioid receptors in the central nervous system, leading to decreased perception of pain and suppression of the cough reflex. Levomethorphan is structurally related to other opioids, which contributes to its potential for abuse and dependence. Due to its pharmacological profile, it is classified as a controlled substance in many jurisdictions. Safety and efficacy profiles are important considerations in its use, as side effects may include sedation, respiratory depression, and gastrointestinal disturbances. As with all opioids, careful monitoring is essential to mitigate risks associated with its use.
Formula:C18H25NO
InChI:InChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17+,18+/m0/s1
InChI key:InChIKey=MKXZASYAUGDDCJ-CGTJXYLNSA-N
SMILES:O(C)C=1C=C2[C@@]34[C@]([C@@](CC2=CC1)(N(C)CC3)[H])(CCCC4)[H]
Synonyms:- (-)-3-methoxy-N-methylmorphinan
- (9Alpha)-3-Methoxy-17-Methylmorphinan
- (9Alpha,13Alpha)-3-Methoxy-17-Methylmorphinan
- 2H-10,4a-Iminoethanophenanthrene, 1,3,4,9,10,10a-hexahydro-6-methoxy-11-methyl-
- 3-Methoxy-17-methylmorphinan
- Methorphan
- Morphinan, 3-methoxy-17-methyl-
- l-Methorphan
- Levomethorphan
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Found 4 products.
Levomethorphan Solution (0.1 mg/mL 3-Methoxy-17-methylmorphinan in methanol)
CAS:Controlled ProductDrugs containing a quinoline or isoquinoline ring-system (whether or not hydrogenated) not further fusedFormula:C18H25NOColor and Shape:Colorless LiquidMolecular weight:271.19361Levomethorphan
CAS:Controlled ProductApplications Levomethorphan is the enantiomer of Dextromethorphan (D299455), an antitussive medicine, a narcotic. Controlled substance.
References Hafliger, et al.: Helv. Chim. Acta, 39, 2053 (1956), Cox, B.M., et al.: Br. J. Pharmacol. Chemother., 27, 81 (1966), Hou, Chia-Hui; Tzeng, J., et al.: Eur. J. Pharmacol., 544, 10 (2006),Formula:C18H25NOColor and Shape:NeatMolecular weight:271.4Levomethorphan (1 mg/ml in Acetonitrile)
CAS:Controlled ProductFormula:C18H25NOColor and Shape:Single SolutionMolecular weight:271.40
