CAS 1252765-13-1

Formula: C26H24FN5O2S

InChI: InChI=1S/C26H24FN5O2S/c27-20-2-4-21(5-3-20)32-9-7-18-15-19(1-6-23(18)32)25(33)31-16-22(17-31)29-10-12-30(13-11-29)26(34)24-28-8-14-35-24/h1-9,14-15,22H,10-13,16-17H2

InChI key: IVOACCSOISMVBL-UHFFFAOYSA-N

SMILES: C1CN(CCN1C2CN(C2)C(=O)C3=CC4=C(C=C3)N(C=C4)C5=CC=C(C=C5)F)C(=O)C6=NC=CS6

JNJ-42226314

CAS: 1252765-13-1

JNJ-42226314

Formula: C₂₆H₂₄FN₅O₂S

Purity: ≥98%

Molecular weight: 489.56

Ref: 54-BUP09558

(1-(4-Fluorophenyl)-1H-indol-5-yl)(3-(4-(thiazole-2-carbonyl)piperazin-1-yl)azetidin-1-yl)methanone

CAS: 1252765-13-1

Purity: 99.62%

Ref: IN-DA01V50O

JNJ-42226314

CAS: 1252765-13-1

(1-(4-Fluorophenyl)-1H-indol-5-yl)(3-(4-(thiazole-2-carbonyl)piperazin-1-yl)azetidin-1-yl)methanone

Formula: C₂₆H₂₄FN₅O₂S

Purity: 99%

Molecular weight: 489.56

Ref: IN-DG01347907

Compound 6g

CAS: 1252765-13-1

Compound 6g is a heterocyclic compound that has been studied for its potential use as an anticancer agent. It has been shown to have a significant cytotoxicity in the plate test and it inhibits cell proliferation in human HL-60 cells. Compound 6g also inhibits the production of inflammatory cytokines, such as TNF-α, IL-1β, and IL-8 by inhibiting the activation of toll-like receptor 4 (TLR4). This molecule also shows inhibitory properties on various biological processes including mitochondrial membrane potential, inhibitor binding, and protein synthesis. Molecular docking analysis has shown that Compound 6g binds to the ATP binding site of bacterial DNA gyrase.

Formula: C₂₆H₂₄FN₅O₂S

Purity: Min. 95%

Molecular weight: 489.16347

Ref: 3D-BC178099

JNJ-42226314

CAS: 1252765-13-1

JNJ-42226314 is a MAGL inhibitor with anti-injury effects and has shown efficacy in neuropathic pain and inflammatory pain models.

Formula: C₂₆H₂₄FN₅O₂S

Purity: 99.74%

Color and Shape: White Solid

Molecular weight: 489.564

Ref: TM-T11724