CAS 1254980-38-5

Formula: C23H25F3N4

InChI: InChI=1S/C23H25F3N4/c24-23(25,26)21-19(10-13-30-20(14-16-6-7-16)27-28-22(21)30)15-29-11-8-18(9-12-29)17-4-2-1-3-5-17/h1-5,10,13,16,18H,6-9,11-12,14-15H2

InChI key: LYDKDODJIBQNLK-UHFFFAOYSA-N

SMILES: C1CC1CC2=NN=C3N2C=CC(=C3C(F)(F)F)CN4CCC(CC4)C5=CC=CC=C5

JNJ-46281222

CAS: 1254980-38-5

JNJ-46281222

Formula: C₂₃H₂₅F₃N₄

Purity: 98.79%

Molecular weight: 414.47

Ref: 54-PC1032187

JNJ-46281222

CAS: 1254980-38-5

Formula: C₂₃H₂₅F₃N₄

Purity: 98.79%

Molecular weight: 414.4666

Ref: IN-DA01V1RM

JNJ-46281222

CAS: 1254980-38-5

JNJ-46281222 is a drug that has been shown to have allosteric modulatory activity at the metabotropic glutamate receptor. It has been shown to decrease the duration of psychosis in animal models, and may be useful for long-term treatment of schizophrenia. JNJ-46281222 binds to the metabotropic glutamate receptor and inhibits glutamate release, leading to decreased symptoms of psychosis. This drug has also been shown to have an onset latency of 4 hours in humans.

Formula: C₂₃H₂₅F₃N₄

Purity: Min. 95%

Molecular weight: 414.5 g/mol

Ref: 3D-EAC98038

JNJ-46281222

CAS: 1254980-38-5

JNJ-46281222: mGlu2-selective, potent PAM, Kd = 1.7 nM, pEC50 = 7.71.

Formula: C₂₃H₂₅F₃N₄

Color and Shape: Solid

Molecular weight: 414.4666

Ref: TM-T15618