CAS 1256585-15-5

Formula: C30H34N4O2

InChI: InChI=1S/C30H34N4O2/c1-4-20-16-23-24(17-26(20)34-9-7-21(8-10-34)33-11-13-36-14-12-33)30(2,3)29-27(28(23)35)22-6-5-19(18-31)15-25(22)32-29/h5-6,15-17,21,32H,4,7-14H2,1-3H3/i11D2,12D2,13D2,14D2

InChI key: KDGFLJKFZUIJMX-FUEQIQQISA-N

SMILES: [2H]C1(C(OC(C(N1C2CCN(CC2)C3=CC4=C(C=C3CC)C(=O)C5=C(C4(C)C)NC6=C5C=CC(=C6)C#N)([2H])[2H])([2H])[2H])([2H])[2H])[2H]

Alectinib-d8

Controlled Product

CAS: 1256585-15-5

Applications Alectinib-d8 is the labelled analogue of Alectinib (C183365, HCl), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth. Also is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth.
References Sakamoto, H., et al.: Cancer Cell., 19, 679 (2011); Kinoshita, K., et al.: Bio-org. Medn., 20, 1271 (2012);

Formula: C₃₀D₈H₂₆N₄O₂

Color and Shape: Neat

Molecular weight: 490.66

Ref: TR-A521182

Alectinib-D8

CAS: 1256585-15-5

Alectinib-D8 is a deuterated compound of Alectinib. Alectinib (T1936) has a CAS number of 1256580-46-7. CH5424802 is an orally available inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with antineoplastic activity.

Formula: C₃₀H₂₆D₈N₄O₂

Molecular weight: 490.67

Ref: TM-TMID-0073

Alectinib-d8

CAS: 1256585-15-5

Formula: C₃₀H₃₄N₄O₂

Molecular weight: 490.7

Ref: BE-RMCA106013

Alectinib-[d8]

CAS: 1256585-15-5

Formula: C₃₀H₃₄N₄O₂

Molecular weight: 490.7

Ref: BE-MD-7717

Alectinib-d8

CAS: 1256585-15-5

Formula: C₃₀H₃₄N₄O₂

Molecular weight: 490.7

Ref: BE-RMCA106005

Alectinib-d8

CAS: 1256585-15-5

Formula: C₃₀H₂₆N₄O₂D₈

Molecular weight: 490.67

Ref: ST-EA-CP-IL0151