CAS 1256589-74-8

5H-Benzo[b]carbazole-3-carbonitrile, 9-ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-, hydrochloride (1:1)

Description:

5H-Benzo[b]carbazole-3-carbonitrile, 9-ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-, hydrochloride (1:1) is a complex organic compound characterized by its multi-ring structure, which includes a benzo[b]carbazole moiety. This compound features a carbonitrile functional group, contributing to its reactivity and potential applications in organic synthesis. The presence of ethyl and dimethyl groups enhances its hydrophobic characteristics, while the morpholine and piperidine substituents may impart specific pharmacological properties, suggesting potential biological activity. As a hydrochloride salt, it is likely to exhibit improved solubility in aqueous environments, which is advantageous for pharmaceutical formulations. The compound's molecular structure indicates potential interactions with biological targets, making it of interest in medicinal chemistry. Its CAS number, 1256589-74-8, allows for precise identification and retrieval of information regarding its properties, synthesis, and applications in scientific literature. Overall, this compound represents a significant structure in the realm of organic and medicinal chemistry, warranting further investigation for its potential uses.

Formula: C₃₀H₃₄N₄O₂·ClH

InChI: InChI=1S/C30H34N4O2.ClH/c1-4-20-16-23-24(17-26(20)34-9-7-21(8-10-34)33-11-13-36-14-12-33)30(2,3)29-27(28(23)35)22-6-5-19(18-31)15-25(22)32-29;/h5-6,15-17,21,32H,4,7-14H2,1-3H3;1H

InChI key: InChIKey=GYABBVHSRIHYJR-UHFFFAOYSA-N

SMILES: O=C1C2=C(C(C)(C)C=3C1=CC(CC)=C(C3)N4CCC(CC4)N5CCOCC5)NC=6C2=CC=C(C#N)C6.Cl

Synonyms:

• 5H-Benzo[b]carbazole-3-carbonitrile, 9-ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-, hydrochloride (1:1)
• Alecensa
• Alectinib HCl
• Alectinib hydrochloride
• Alectinib hydrochloride

Alectinib Hydrochloride

CAS: 1256589-74-8

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₃₀H₃₄N₄O₂·HCl

Color and Shape: White Yellow Powder

Molecular weight: 482.26818

Ref: 45-1012775

Alectinib Hydrochloride

CAS: 1256589-74-8

Alectinib Hydrochloride

Formula: C₃₀H₃₅ClN₄O₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 519.08

Ref: 54-OR1027430

5H-Benzo[b]carbazole-3-carbonitrile, 9-ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-, hydrochloride (1:1)

CAS: 1256589-74-8

Formula: C₃₀H₃₅ClN₄O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 519.0775

Ref: IN-DA000OAG

Alectinib hydrochloride

CAS: 1256589-74-8

Alectinib hydrochloride

Formula: C₃₀H₃₅ClN₄O₂

Purity: ≥98%

Molecular weight: 519.08

Ref: 54-BUP10294

Alectinib HCl

CAS: 1256589-74-8

9-Ethyl-6,6-dimethyl-8-(4-morpholin-4-ylpiperidin-1-yl)-11-oxo-5H-benzo[B]carbazole-3-carbonitrile,hydrochloride

Formula: C₃₀H₃₅ClN₄O₂

Purity: 98%

Molecular weight: 519.08

Ref: IN-DG304688

Alectinib hydrochloride

CAS: 1256589-74-8

Alectinib hydrochloride (RO5424802 Hydrochloride) is a selective, and orally available inhibitor of ALK( IC50 : 1.9 nM)

Formula: C₃₀H₃₅ClN₄O₂

Purity: 99.74% - 99.96%

Color and Shape: Solid

Molecular weight: 519.08

Ref: TM-T8387

Alectinib Hydrochloride

CAS: 1256589-74-8

Formula: C₃₀H₃₄N₄O₂HCl

Molecular weight: 482.6 : 36.46

Ref: ST-EA-CP-A118002

CH5424802 (Alectinib) Hydrochloride

Controlled Product

CAS: 1256589-74-8

Applications CH5424802 Hydrochloride is a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth. Also is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth.
References Sakamoto, H., et al.: Cancer Cell., 19, 679 (2011); Kinoshita, K., et al.: Bio-org. Medn., 20, 1271 (2012);

Formula: C₃₀H₃₄N₄O₂·ClH

Color and Shape: Neat

Molecular weight: 519.08

Ref: TR-C183365

Alectinib hydrochloride

CAS: 1256589-74-8

An active product of vitamin A metabolism. Activates RXR and RAR receptor isoforms with high binding affinity. Induces differentiation of neural stem cells into neurons.

Formula: C₃₀H₃₄N₄O₂·HCl

Purity: Min. 95%

Color and Shape: Off-White To Beige Solid

Molecular weight: 519.08 g/mol

Ref: 3D-FA64934

Alectinib hydrochloride

CAS: 1256589-74-8

Purity: 98%

Molecular weight: 518.245

Ref: 10-F865555