CAS 1260075-17-9: Mitapivat

Description: Mitapivat is a small molecule drug primarily used in the treatment of certain types of hemolytic anemia, particularly pyruvate kinase deficiency. It acts as a pyruvate kinase activator, enhancing the glycolytic pathway and promoting red blood cell survival by improving energy metabolism. The chemical structure of Mitapivat includes a pyrimidine core, which is essential for its biological activity. It is characterized by its ability to increase ATP production in red blood cells, thereby alleviating symptoms associated with anemia. Mitapivat is administered orally and has been shown to have a favorable pharmacokinetic profile, with a relatively long half-life that allows for once-daily dosing. Its safety and efficacy have been evaluated in clinical trials, demonstrating significant improvements in hemoglobin levels and overall patient quality of life. As with any medication, potential side effects may include headache, fatigue, and gastrointestinal disturbances, necessitating monitoring during treatment. Overall, Mitapivat represents a novel therapeutic approach for managing hemolytic anemia linked to pyruvate kinase deficiency.

Synonyms:

• N-(4-{[4-(Cyclopropylmethyl)-1-piperazinyl]carbonyl}phenyl)-8-quinolinesulfonamide
• N-(4-(4-(cyclopropylmethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide

Mitapivat

CAS: 1260075-17-9

• Formula: C₂₄H₂₆N₄O₃S
• Molecular weight: 450.56

Mitapivat

CAS: 1260075-17-9

• Purity: ≥98%
• Molecular weight: 450.55g/mol

Mitapivat-d8

CAS: 1260075-17-9

• Formula: C₂₄H₁₈D₈N₄O₃S
• Molecular weight: 458.61

Mitapivat

CAS: 1260075-17-9

Mitapivat (PKR-IN-1), also known as PKM2 activator 1020 is a PKM2 activator (pyruvate kinase activator) …

• Formula: C₂₄H₂₆N₄O₃S
• Purity: 99.47% - 99.83%
• Color and Shape: Solid
• Molecular weight: 450.55

Mitapivat

CAS: 1260075-17-9

• Formula: C₂₄H₂₆N₄O₃S
• Color and Shape: Neat

Mitapivat

CAS: 1260075-17-9

Please enquire for more information about Mitapivat including the price, delivery time and more detailed …

• Formula: C₂₄H₂₆N₄O₃S
• Purity: Min. 95%
• Molecular weight: 450.55 g/mol

PKR-IN-1

CAS: 1260075-17-9

• Formula: C₂₄H₂₆N₄O₃S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 450.5532