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CAS 1260075-17-9: Mitapivat
Description:Mitapivat is a small molecule drug primarily used in the treatment of certain types of hemolytic anemia, particularly pyruvate kinase deficiency. It acts as a pyruvate kinase activator, enhancing the glycolytic pathway and promoting red blood cell survival by improving energy metabolism. The chemical structure of Mitapivat includes a pyrimidine core, which is essential for its biological activity. It is characterized by its ability to increase ATP production in red blood cells, thereby alleviating symptoms associated with anemia. Mitapivat is administered orally and has been shown to have a favorable pharmacokinetic profile, with a relatively long half-life that allows for once-daily dosing. Its safety and efficacy have been evaluated in clinical trials, demonstrating significant improvements in hemoglobin levels and overall patient quality of life. As with any medication, potential side effects may include headache, fatigue, and gastrointestinal disturbances, necessitating monitoring during treatment. Overall, Mitapivat represents a novel therapeutic approach for managing hemolytic anemia linked to pyruvate kinase deficiency.
- Synonyms:
- N-(4-{[4-(Cyclopropylmethyl)-1-piperazinyl]carbonyl}phenyl)-8-quinolinesulfonamide
- N-(4-(4-(cyclopropylmethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide
Brand | Product data | Purity | Price range | Estimated delivery |
---|---|---|---|---|
![]() | Mitapivat REF: 4Z-M-307001CAS: 1260075-17-9 | - - - | To inquire | Fri 07 Mar 25 |
![]() | Mitapivat-d8 REF: 4Z-M-307002CAS: 1260075-17-9 | - - - | To inquire | Fri 07 Mar 25 |
![]() | Mitapivat REF: TM-T4223CAS: 1260075-17-9 | 99.81% - 99.83% | 40.00 €~1,216.00 € | Thu 13 Mar 25 |
![]() | Mitapivat REF: TR-M299830CAS: 1260075-17-9 | - - - | 139.00 €~971.00 € | Tue 18 Mar 25 |
![]() | Mitapivat REF: 3D-KAC07517CAS: 1260075-17-9 | Min. 95% | 188.00 €~1,364.00 € | Mon 17 Mar 25 |
![]() | PKR-IN-1 REF: IN-DA009CJPCAS: 1260075-17-9 | 98% | - - - | Discontinued product |
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Ref: 4Z-M-307001
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |
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Ref: 4Z-M-307002
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |
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Mitapivat
Ref: TM-T4223
1mg | 40.00 € | ||
5mg | 88.00 € | ||
10mg | 126.00 € | ||
25mg | 225.00 € | ||
50mg | 378.00 € | ||
100mg | 560.00 € | ||
500mg | 1,216.00 € |
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Ref: TR-M299830
10mg | 139.00 € | ||
50mg | 556.00 € | ||
100mg | 971.00 € |
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Mitapivat
Ref: 3D-KAC07517
2mg | 304.00 € | ||
5mg | 475.00 € | ||
10mg | 676.00 € | ||
25mg | 1,047.00 € | ||
50mg | 1,364.00 € |
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Ref: IN-DA009CJP
1mg | Discontinued | Request information | |
5mg | Discontinued | Request information | |
10mg | Discontinued | Request information | |
25mg | Discontinued | Request information | |
50mg | Discontinued | Request information | |
100mg | Discontinued | Request information | |
250mg | Discontinued | Request information |