CAS 1260181-14-3

Formula: C27H25F3N4O4

InChI: InChI=1S/C27H25F3N4O4/c1-26(2,38)25(37)34-11-9-33(10-12-34)15-7-8-19(27(28,29)30)17(13-15)21-22(24(36)32-23(21)35)18-14-31-20-6-4-3-5-16(18)20/h3-8,13-14,31,38H,9-12H2,1-2H3,(H,32,35,36)

InChI key: CLGRAWDGLMENOD-UHFFFAOYSA-N

SMILES: CC(C)(C(=O)N1CCN(CC1)C2=CC(=C(C=C2)C(F)(F)F)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54)O

3-(5-(4-(2-Hydroxy-2-methylpropanoyl)piperazin-1-yl)-2-(trifluoromethyl)phenyl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione

CAS: 1260181-14-3

3-(5-(4-(2-Hydroxy-2-methylpropanoyl)piperazin-1-yl)-2-(trifluoromethyl)phenyl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione

Formula: C₂₇H₂₅F₃N₄O₄

Purity: 98%

Molecular weight: 526.52

Ref: 54-PC1007763

3-(5-(4-(2-Hydroxy-2-methylpropanoyl)piperazin-1-yl)-2-(trifluoromethyl)phenyl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione

CAS: 1260181-14-3

Purity: 98%

Ref: IN-DA009FP5

TCS-21311

Controlled Product

CAS: 1260181-14-3

Formula: C₂₇H₂₅F₃N₄O₄

Color and Shape: Neat

Molecular weight: 526.507

Ref: TR-T012650

TCS 21311

CAS: 1260181-14-3

Inhibitor of Janus kinase JAK3

Formula: C₂₇H₂₅F₃N₄O₄

Purity: Min. 95%

Molecular weight: 526.51 g/mol

Ref: 3D-FT28015

TCS 21311

CAS: 1260181-14-3

TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective over JAK1, JAK2, TYK2.

Formula: C₂₇H₂₅F₃N₄O₄

Purity: 99.39% - ≥98%

Color and Shape: Solid

Molecular weight: 526.51

Ref: TM-T17019