CAS 12650-69-0
:Mupirocin
Description:
Mupirocin is a topical antibiotic primarily used for the treatment of skin infections caused by certain bacteria, particularly Staphylococcus aureus, including methicillin-resistant strains (MRSA). It is derived from the fermentation of the bacterium Pseudomonas fluorescens. Mupirocin functions by inhibiting bacterial protein synthesis through binding to isoleucyl-tRNA synthetase, which disrupts the incorporation of isoleucine into proteins, ultimately leading to bacterial cell death. The substance is typically available in ointment or cream form and is applied directly to the affected area. Mupirocin is known for its low systemic absorption when used topically, making it effective for localized infections with minimal risk of systemic side effects. It is generally well-tolerated, although some patients may experience local irritation or allergic reactions. Due to its specific mechanism of action and effectiveness against resistant strains, mupirocin is an important option in the management of skin infections and is often used in both outpatient and hospital settings.
Formula:C26H44O9
InChI:InChI=1S/C26H44O9/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29)/b16-13+/t17-,18-,19-,20-,21-,24+,25-,26-/m0/s1
InChI key:InChIKey=MINDHVHHQZYEEK-HBBNESRFSA-N
SMILES:C([C@H]1[C@]([C@H]([C@H](C)O)C)(O1)[H])[C@@H]2[C@@H](O)[C@@H](O)[C@H](C/C(=C/C(OCCCCCCCCC(O)=O)=O)/C)OC2
Synonyms:- (E)-(2S,3R,4R,5S)-5-((2S,3S,4S,5S)-2,3-Epoxy-5-hydroxy-4-methylhexyl)tetrahydro-3,4-dihydroxy-beta-methyl-2H-pyran-2-crotonic acid, ester with 9-hydroxynonanoic acid
- 8-Carboxyoctyl (E)-4-(2S,3R,4R,5S)-5-((2S,3S,4S,5S)-2,3-epoxy-5-hydroxy-4-methylhexyl)-3,4-dihydroxytetrahydro-2H-pyran-2-yl)-3-methylcrotonat
- 9-({(2E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-({(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl}methyl)tetrahydro-2H-pyran-2-yl]-3-methylbut-2-enoyl}oxy)nonanoic acid (non-preferred name)
- <span class="text-smallcaps">L</span>-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, (2E)-
- <span class="text-smallcaps">L</span>-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[3-(2-hydroxy-1-methylpropyl)oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, [2E,8[2S,3S(1S,2S)]]-
- Bactoderm
- Bactroban
- Bactroban Ointment
- Brl 4910A
- Centany
- L-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, (2E)-
- L-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[3-(2-hydroxy-1-methylpropyl)oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, [2E,8[2S,3S(1S,2S)]]-
- Mupirocin Neo-Sensitabs
- Mupirocin [USAN:INN:BAN]
- Mupirocina
- Mupirocina [Spanish]
- Mupirocine
- Mupirocine [French]
- Mupirocinum
- Mupirocinum [Latin]
- Mupricin
- Nonanoic acid, 9-((3-methyl-1-oxo-4-(tetrahydro-3,4-dihydroxy-5-((3-(2-hydroxy-1-methylpropyl)oxiranyl)methyl)-2H-pyran-2-yl)-2-butenyl)oxy)-, (2S-(2alpha(E),3beta,4beta,5alpha(2R*,3R*(1R*,2R*))))-
- Nonanoic acid, 9-[[(2Z)-3-methyl-1-oxo-4-[(2S,3R,4R,5S)-tetrahydro-3,4-dihydroxy-5-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]-2-oxiranyl]methyl]-2H-pyran-2-yl]-2-buten-1-yl]oxy]-
- Plasimine
- Pseudomonic acid
- Pseudomonic acid A
- Turixin
- Unii-D0Gx863Oa5
- See more synonyms
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Mupirocin
CAS:Formula:C26H44O9Purity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:500.63Mupirocin, 92%
CAS:Mupirocin is involved in inhibition of protein synthesis was reversed by isoleucine and Pseudomonic Acid was shown to inhibit IleRS (isoleucyl-tRNA synthetase) in vitro. It also demonstrates weak inhibitory action on FARSL (phenylalanyl-tRNA synthetase). Efficacy against staphylococci and streptococFormula:C26H44O9Purity:92%Molecular weight:500.63Mupirocin
CAS:Antibiotics nesoiFormula:C26H44O9Color and Shape:White PowderMolecular weight:500.29853Mupirocin
CAS:Mupirocin (BRL-4910A) is a RNA synthetase inhibitor antibacterial. It has shown excellent activity against gram-positive staphylococci and streptococci.Formula:C26H44O9Purity:97.37% - 97.46%Color and Shape:SolidMolecular weight:500.62Mupirocin
CAS:Formula:C26H44O9Purity:920 - 1020 μg/mg (anhydrous)Color and Shape:White to off-white powderMolecular weight:500.63Mupirocin
CAS:MupirocinFormula:C26H44O9Purity:920-1020μgmgColor and Shape:SolidMolecular weight:500.63Ref: IN-DA000SV0
100mg24.00€1g25.00€250mg28.00€5g52.00€10g67.00€25g111.00€50g198.00€100g301.00€1kg904.00€Mupirocin
CAS:Controlled ProductApplications Mupirocin, is a major component of the pseudomonic acid, an antibiotic complex produced by Pseudomonas fluorescens NCIB 10586. Topical antibacterial.
References Hughes, J., et al.: J. Antibiot., 31, 330 (1978), Ward, A., et al.: Drugs, 32, 425 (1986), Casewell, M.W., et al.: J. Antimicrob. Chemother., 19, 1 (1987),Formula:C26H44O9Color and Shape:NeatMolecular weight:500.62Mupirocin
CAS:Inhibitor of isoleucyl-tRNA synthetase; inhibitor of protein synthesisFormula:C26H44O9Purity:Min. 92 Area-%Color and Shape:White PowderMolecular weight:500.62 g/mol9-(((E)-4-((2S,3R,4R,5S)-3,4-Dihydroxy-5-(((2S,3S)-3-((2S,3S)-3-hydroxybutan-2-yl)oxiran-2-yl)methyl)tetrahydro-2H-pyran-2-yl)-3-methylbut-2-enoyl)oxy)nonanoic acid
CAS:9-(((E)-4-((2S,3R,4R,5S)-3,4-Dihydroxy-5-(((2S,3S)-3-((2S,3S)-3-hydroxybutan-2-yl)oxiran-2-yl)methyl)tetrahydro-2H-pyran-2-yl)-3-methylbut-2-enoyl)oxy)nonanoic acidFormula:C26H44O9Purity:95%Molecular weight:500.62Mupirocin
CAS:9-(((E)-4-((2S,3R,4R,5S)-3,4-Dihydroxy-5-(((2S,3S)-3-((2S,3S)-3-hydroxybutan-2-yl)oxiran-2-yl)methyl)tetrahydro-2H-pyran-2-yl)-3-methylbut-2-enoyl)oxy)nonanoic acidFormula:C26H44O9Purity:920μg/mg-1020μg/mgMolecular weight:500.62
