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CAS 1268494-46-7

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Tigecycline (open C-ring D-ring) Quinone

Description:
Tigecycline (open C-ring D-ring) quinone, identified by the CAS number 1268494-46-7, is a derivative of tigecycline, which is a glycylcycline antibiotic. This compound exhibits a broad spectrum of antibacterial activity, particularly against multidrug-resistant Gram-positive and Gram-negative bacteria. The open C-ring and D-ring structure of this compound suggests modifications that may influence its pharmacological properties, such as enhanced stability and bioavailability. Tigecycline itself is known for its ability to inhibit protein synthesis by binding to the 30S ribosomal subunit, thereby preventing the incorporation of amino acids into peptides. The quinone moiety may also contribute to its reactivity and potential interactions with biological systems. In terms of solubility, tigecycline derivatives typically exhibit moderate solubility in aqueous solutions, which is essential for their therapeutic efficacy. Overall, the unique structural features of tigecycline (open C-ring D-ring) quinone may provide insights into its mechanism of action and potential applications in treating resistant bacterial infections.
Formula:C26H32N4O8
Synonyms:
  • Tigecycline Impurity 2(Tigecycline quinone analog)
  • Tigecycline (open C-ring D-ring) Quinone (Technical Grade)
  • Tigecycline Quinone Impurity
  • Tigecycline USP Impurity F
  • DISCONTINUED. Please see T440035
  • Tigecycline Quinone Analogue
  • 4-[[(2S)-6-[[2-(tert-butylamino)acetyl]amino]-8-(dimethylamino)-5-hydroxy-4-oxo-2,3-dihydro-1H-naphthalen-2-yl]methyl]-2,5-dihydroxy-3,6-dioxocyclohexa-1,4-diene-1-carboxamide
  • Tigecycline Impurity 9
  • (S)-4-((6-(2-(tert-butylamino)acetamido)
  • Tigecycline Impurity 4
  • See more synonyms
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