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CAS 127-69-5

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Sulfisoxazole

Description:
Sulfisoxazole is a sulfonamide antibiotic characterized by its ability to inhibit bacterial growth by interfering with the synthesis of folic acid, which is essential for bacterial metabolism. It is a white to off-white crystalline powder that is soluble in water and exhibits a slightly bitter taste. The chemical formula of sulfisoxazole is C10H10N4O3S, and it has a molecular weight of approximately 246.27 g/mol. This compound is primarily used in the treatment of urinary tract infections and other bacterial infections, often in combination with other medications to enhance its efficacy. Sulfisoxazole works by mimicking para-aminobenzoic acid (PABA), a substrate for bacterial folate synthesis, thereby disrupting the production of folate. It is important to note that while effective, sulfisoxazole may cause side effects, including allergic reactions and gastrointestinal disturbances. As with all antibiotics, it is crucial to use sulfisoxazole judiciously to prevent the development of antibiotic resistance.
Formula:C11H13N3O3S
InChI:InChI=1S/C11H13N3O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6,14H,12H2,1-2H3
InChI key:InChIKey=NHUHCSRWZMLRLA-UHFFFAOYSA-N
SMILES:S(NC1=C(C)C(C)=NO1)(=O)(=O)C2=CC=C(N)C=C2
Synonyms:
  • 3,4-Dimethyl-5-sulfanilamidoisoxazole
  • 3,4-Dimethyl-5-sulfonamidoisoxazole
  • 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide
  • 4-Amino-N-(3,4-dimethylisoxazol-5-yl)benzenesulfonamide
  • 4-amino-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide
  • 5-(4-Aminophenylsulfonamido)-3,4-dimethylisoxazole
  • 5-(p-Aminobenzenesulfonamido)-3,4-dimethylisoxazole
  • 5-(p-Aminobenzenesulphonamido)-3,4-dimethylisoxazole
  • 5-Sulfanilamido-3,4-dimethylisoxazole
  • Alphazole
  • See more synonyms
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