CAS 127-74-2

Acetylsulfadiazine

Description:

Acetylsulfadiazine, with the CAS number 127-74-2, is a sulfonamide antibiotic that is primarily used in veterinary medicine. It is characterized by its sulfonamide structure, which includes a sulfonyl group attached to an aromatic amine. This compound exhibits antibacterial properties by inhibiting bacterial folic acid synthesis, which is essential for their growth and reproduction. Acetylsulfadiazine is typically administered in its acetylated form, enhancing its solubility and absorption. It is often used to treat infections in animals, particularly in poultry and livestock. The substance is generally stable under normal conditions but should be stored in a cool, dry place away from light to maintain its efficacy. As with many sulfonamides, it may cause allergic reactions in some individuals, and its use is subject to regulations in food-producing animals to prevent residues in meat and milk. Overall, acetylsulfadiazine is an important compound in the field of veterinary pharmacology, contributing to the management of bacterial infections in animals.

Formula: C₁₂H₁₂N₄O₃S

InChI: InChI=1/C12H12N4O3S/c1-9(17)15-10-3-5-11(6-4-10)20(18,19)16-12-13-7-2-8-14-12/h2-8H,1H3,(H,15,17)(H,13,14,16)

InChI key: InChIKey=NJIZUWGMNCUKGU-UHFFFAOYSA-N

SMILES: S(NC=1N=CC=CN1)(=O)(=O)C2=CC=C(NC(C)=O)C=C2

Synonyms:

• 2-[(p-Acetamidophenyl)sulfonamido]pyrimidine
• 4′-(2-Pyrimidinylsulfamoyl)acetanilide
• AC-sulfadiazine
• Acetamide, N-[4-[(2-pyrimidinylamino)sulfonyl]phenyl]-
• Acetanilide, 4′-(2-pyrimidinylsulfamoyl)-
• Acetylsulfadiazine
• N-Acetylsulfadiazine
• N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide
• N-[4-[(2-Pyrimidinylamino)sulfonyl]phenyl]acetamide
• N4-acetylsulfadiazine
• N⁴-Acetylsulfadiazine
• N(4)-acetylsulfadiazine
• N-[4-(Pyrimidin-2-ylsulfamoyl)pheny
• N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide(acetylsulfadiazine)
• Sulfadiazine Impurity 5 (Sulfadiazine EP Impurity E)
• Acetylsulfadiazine CRS
• 4N-Acetylsulfadiazine
• N-(4-(N-(pyrimidin-2-yl)sulfamoyl)phenyl)acetamide
• 4'-(pyrimidin-2-ylsulphamoyl)acetanilide
• Sulfadiazine EP Impurity E
• Sulfadiazine Impurity E
• Sulfadiazine N-Acetyl Impurity/Sulfadiazine Impurity E
• N-(4-(N-(Pyrimidin-2-yl)sulfamoyl)phenyl)acetamide (Sulfadiazine Impurity)

ACETYLSULFADIAZINE CRS

CAS: 127-74-2

ACETYLSULFADIAZINE CRS

Formula: C₁₂H₁₂N₄O₃S

Molecular weight: 292.3137

Ref: 41-Y0001462

N-((4-Aminophenyl)sulfonyl)-N-(pyrimidin-2-yl)acetamide

CAS: 127-74-2

N-((4-Aminophenyl)sulfonyl)-N-(pyrimidin-2-yl)acetamide

Formula: C₁₂H₁₂N₄O₃S

Purity: ≥93%

Molecular weight: 292.31

Ref: 54-OR1127918

Sulfadiazine EP Impurity E

CAS: 127-74-2

Formula: C₁₂H₁₂N₄O₃S

Color and Shape: White To Off-White Solid

Molecular weight: 292.31

Ref: 4Z-S-096

N-((4-Aminophenyl)sulfonyl)-N-(pyrimidin-2-yl)acetamide

CAS: 127-74-2

Formula: C₁₂H₁₂N₄O₃S

Purity: 93%

Color and Shape: Solid

Molecular weight: 292.3137

Ref: IN-DA000WJO

Sulfadiazine-N-acetyl

CAS: 127-74-2

Formula: C₁₂H₁₂N₄O₃S

Color and Shape: Neat

Molecular weight: 292.31

Ref: 04-C16990520

N-[4-(Pyrimidin-2-ylsulfamoyl)phenyl]acetamide (Acetylsulfadiazine)

Controlled Product

CAS: 127-74-2

Formula: C₁₂H₁₂N₄O₃S

Color and Shape: Neat

Molecular weight: 292.31

Ref: 86-MM0623.02

N-Acetyl Sulfadiazine

Controlled Product

CAS: 127-74-2

Formula: C₁₂H₁₂N₄O₃S

Color and Shape: Neat

Molecular weight: 292.31

Ref: TR-A187810

N-Acetyl sulfadiazine

CAS: 127-74-2

N-Acetyl sulfadiazine is a sulfonamide drug that is used to treat urinary tract infections and bowel diseases. It is an antibacterial and anti-inflammatory agent. N-Acetyl sulfadiazine is prepared by reacting sulfadiazine with acetyl chloride in the presence of hydrochloric acid, followed by purification by preparative high-performance liquid chromatography (prep-HPLC) or preparative thin layer chromatography (prep-TLC). N-Acetyl sulfadiazine has been shown to inhibit particle formation in vitro and can be used as a particle probe for inflammatory bowel disease.

Formula: C₁₂H₁₂N₄O₃S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 292.31 g/mol

Ref: 3D-FA17043

Sulfadiazine EP Impurity E

CAS: 127-74-2

Formula: C₁₂H₁₂N₄O₃S

Molecular weight: 292.31

Ref: ST-EA-CP-S54005