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CAS 1272755-33-5

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Fmoc-D-Lys(ivDde)-OH

Description:
Fmoc-D-Lys(ivDde)-OH is a chemical compound commonly used in peptide synthesis, particularly in the field of medicinal chemistry and biochemistry. It features a protected form of the amino acid lysine, where the Fmoc (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino functionality, allowing for selective reactions at the carboxyl end. The "D" indicates that the lysine is in its D-enantiomer form, which is important for specific biological activity and interactions. The "ivDde" refers to an additional protective group, specifically the 1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl group, which is used to protect the side chain amine of lysine during synthesis. This compound is typically utilized in solid-phase peptide synthesis, enabling the construction of peptides with precise sequences and modifications. Its stability under various reaction conditions and compatibility with coupling reagents make it a valuable building block in the synthesis of complex peptides and peptidomimetics.
Formula:C34H42N2O6
InChI:InChI=1S/C34H42N2O6/c1-21(2)17-28(31-29(37)18-34(3,4)19-30(31)38)35-16-10-9-15-27(32(39)40)36-33(41)42-20-26-24-13-7-5-11-22(24)23-12-6-8-14-25(23)26/h5-8,11-14,21,26-27,37H,9-10,15-20H2,1-4H3,(H,36,41)(H,39,40)/t27-/m1/s1
InChI key:LHJJUCZESVFWSO-HHHXNRCGSA-N
SMILES:CC(C)CC(=NCCCC[C@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)C4=C(CC(CC4=O)(C)C)O
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