CAS 127913-44-4

(S)-(-)-4-chloro 3-hydroxybutyronitrile

Formula: C₄H₆ClNO

InChI: InChI=1/C4H6ClNO/c5-3-4(7)1-2-6/h4,7H,1,3H2/t4-/m0/s1

SMILES: C(C#N)[C@@H](CCl)O

Synonyms:

• S-(-)-4-chloro-3-hydorxy butyronitrile
• (3S)-4-chloro-3-hydorxybutyronitrile
• (3R)-4-chloro-3-hydroxybutanenitrile
• (3S)-4-chloro-3-hydroxybutanenitrile

(S)-(-)-4-Chloro-3-hydroxybutyronitrile

CAS: 127913-44-4

Formula: C₄H₆ClNO

Purity: >98.0%(GC)

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 119.55

Ref: 3B-C3331

Butanenitrile, 4-chloro-3-hydroxy-, (3S)-

CAS: 127913-44-4

Formula: C₄H₆ClNO

Purity: 98%

Color and Shape: Liquid

Molecular weight: 119.5495

Ref: IN-DA000XKP

(S)-4-Chloro-3-hydroxybutyronitrile

CAS: 127913-44-4

(S)-4-Chloro-3-hydroxybutyronitrile

Formula: C₄H₆ClNO

Purity: 98%

Color and Shape: Liquid

Molecular weight: 119.54954

Ref: 54-OR912506

(S)-4-Chloro-3-hydroxybutyronitrile

CAS: 127913-44-4

Formula: C₄H₆ClNO

Purity: 97%

Color and Shape: Liquid

Molecular weight: 119.55

Ref: 10-F092339

(3S)-4-Chloro-3-hydroxybutyronitrile

Controlled Product

CAS: 127913-44-4

Applications (3S)-4-Chloro-3-hydroxybutyronitrile is used in various organic precursor syntheses. It is used in the synthesis of hydroxypyrrolidinones to by used as carbapenem precursors. Also used in the preparation of atorvastatin (A791750) precursors. Impurity in the synthesis of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor. Antilipemic.
References Kanno, O. et al.: Hetero., 53, 173 (2000); Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997), Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005), Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006); Jiang, C. et al.: Lett. Org. Chem., 9, 520 (2012);

Formula: C₄H₆ClNO

Color and Shape: Neat

Molecular weight: 119.55

Ref: TR-C366605

Rosuvastatin Impurity 13

CAS: 127913-44-4

Formula: C₄H₆ClNO

Molecular weight: 119.55

Ref: ST-EA-CP-R1092