CAS 128-13-2

Ursodeoxycholic acid

Description:

Ursodeoxycholic acid (UDCA), with the CAS number 128-13-2, is a bile acid that is naturally occurring in the body, primarily synthesized from cholesterol. It is characterized by its hydrophilic properties, which make it less toxic than other bile acids. UDCA is known for its ability to promote the solubilization of cholesterol in bile, thereby aiding in the prevention of cholesterol gallstone formation. It has been utilized therapeutically to treat various liver diseases, including primary biliary cholangitis and certain forms of cholestasis. The compound exhibits a unique structure, featuring a hydroxyl group at the 7-position, which contributes to its solubility and biological activity. Additionally, UDCA has anti-inflammatory and immunomodulatory effects, making it beneficial in managing liver-related conditions. Its mechanism of action involves enhancing bile flow and reducing the toxicity of bile acids, which can be particularly advantageous in liver dysfunction. Overall, ursodeoxycholic acid is a significant compound in both clinical and biochemical contexts, reflecting its importance in gastrointestinal health and disease management.

Formula: C₂₄H₄₀O₄

InChI: InChI=1/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/p-1/t14-,15-,16-,17-,18+,19+,20+,22+,23+,24-/m1/s1

InChI key: InChIKey=RUDATBOHQWOJDD-UZVSRGJWSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](C[C@@H]3O)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H]

Synonyms:

• (3α,5β,7β)-3,7-Dihydroxycholan-24-oic acid
• 17β-(1-Methyl-3-carboxypropyl)etiocholane-3α,7β-diol
• 3α,7β-Dihydroxy-5β-cholan-24-oate
• 3α,7β-Dihydroxy-5β-cholan-24-oic acid
• 3α,7β-Dihydroxy-5β-cholanic acid
• 3α,7β-Dihydroxy-5β-cholanoic acid
• 3α,7β-Dihydroxycholanic acid
• 5β-Cholan-24-oic acid, 3α,7β-dihydroxy-
• 5β-Cholanic acid, 3α,7β-dihydroxy-
• 7β-Hydroxylithocholic acid
• Acide Ursodesoxycholique
• Acido Ursodeoxicolico
• Actigall
• Adursal
• Arsacol
• CHOLON-24-OIC ACID, 3,7-DIHYDROXY-(3α, 5β, 7.β)-
• Cholit-Ursan
• Delursan
• Desocol
• Desol
• Destolit
• Deursil
• Litursol
• Lyeton
• Nsc 683769
• Paptarom
• Solutrat
• Udca
• Urdes
• Urosiol
• Ursacol
• Ursic acid
• Urso
• Ursobilin
• Ursochol
• Ursocholic acid, deoxy-
• Ursocol
• Ursodamor
• Ursodeoxycholic Acid
• Ursodeoxycholsaure
• Ursodesoxycholic acid
• Ursodiol
• Ursofalk
• Ursogall
• Ursolvan
• Ursosan
• (4R)-4-[(3R,5S,7S,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
• (3alpha,5beta,7beta)-3,7-dihydroxycholan-24-oic acid
• 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethanol
• (4R)-4-[(3R,5S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
• (3alpha,5alpha,7beta)-3,7-dihydroxycholan-24-oate
• (3alpha,5beta,7beta)-3,7-dihydroxycholan-24-oate
• 3alpha,7beta-Dihydroxy-6beta-cholan-24-oic acid
• (3alpha,5beta,7beta,8xi,9xi,14xi)-3,7-dihydroxycholan-24-oic acid
• Cholan-24-oic acid, 3,7-dihydroxy-, (3α,5β,7β)-
• (3alpha,5beta,7alpha)-3,7-dihydroxycholan-24-oic acid
• 3,7-Dihydroxycholan-24-oic acid
• 5BETA-CHOLANIC ACID-3ALPHA,7BETA-DIOL
• 3,7-dihydroxy-,(3-alpha,5-beta,7-beta)-cholan-24-oicaci
• 17-beta-(1-methyl-3-carboxypropyl)etiocholane-3-alpha,7-beta-diol
• 3ALPHA, 7BETA-DIOXYCHOLANIC ACID
• 5BETA-CHOLAN-24-OIC ACID-3ALPHA, 7BETA-DIOL
• (6-BETA)-CHOLANIC ACID-(3-ALPHA)-(7-BETA)-DIOL
• UDCS
• 6BETA-CHOLANIC ACID-3A,7BETA-DIOL
• 3ALPHA, 7BETA-DIHYDROXY-5BETA-CHOLANIC ACID
• 3ALPHA,7BETA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID
• 7BETA-HYDROXYLITHOCHOLIC ACID
• 3-alpha,7-beta-dihydroxy-5-beta-cholan-24-oicaci

Ursodeoxycholic Acid

CAS: 128-13-2

Formula: C₂₄H₄₀O₄

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystaline

Molecular weight: 392.58

Ref: 3B-U0030

Ursodeoxycholic acid, 99%

CAS: 128-13-2

A secondary bile acid This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand tr

Formula: C₂₄H₄₀O₄

Purity: 99%

Color and Shape: Crystals or powder or crystalline powder, White

Molecular weight: 392.58

Ref: 02-B20490

URSODEOXYCHOLIC ACID CRS

CAS: 128-13-2

URSODEOXYCHOLIC ACID CRS

Ref: 41-U0800000

Ursodeoxycholic acid impurity standard

CAS: 128-13-2, 4651-67-6

Ursodeoxycholic acid impurity standard

Color and Shape: Off-White

Ref: 47-1142

Ursodeoxycholic acid

CAS: 128-13-2

Ursodeoxycholic acid

Formula: C₂₄H₄₀O₄

Purity: 99.7%

Color and Shape: White. To. Off-White

Molecular weight: 392.29266

Ref: 47-706

URSODEOXYCHOLIC ACID FOR SYSTEM SUITABILITY CRS

CAS: 128-13-2

URSODEOXYCHOLIC ACID FOR SYSTEM SUITABILITY CRS

Formula: C₂₄H₄₀O₄

Molecular weight: 392.572

Ref: 41-Y0001163

Ursodiol

CAS: 128-13-2

Carboxylic acids w/ alcohol function but w/o other oxygen function and their derivatives, nesoi

Formula: C₂₄H₄₀O₄

Color and Shape: White Off-White Powder

Molecular weight: 392.29266

Ref: 45-1707806

Cholan-24-oic acid, 3,7-dihydroxy-, (3a,5b,7b)-

CAS: 128-13-2

Formula: C₂₄H₄₀O₄

Purity: 99%

Color and Shape: Solid

Molecular weight: 392.5720

Ref: IN-DA00HRR5

Ursodeoxycholic acid

CAS: 128-13-2

Ursodeoxycholic acid (UDCA) is a potent inhibitor of liver-specific fatty acid transporter 5 (FATP5),inhibits cholesterol absorption. High-Quality, Low-Cost!

Formula: C₂₄H₄₀O₄

Purity: 99.74% - ≥95%

Color and Shape: White - Almost White Solid Powder

Molecular weight: 392.57

Ref: TM-T0700

Ursodiol (Ursodeoxycholic Acid)

CAS: 128-13-2

Formula: C₂₄H₄₀O₄

Color and Shape: White To Off-White Solid

Molecular weight: 392.58

Ref: 4Z-U-025

Ursodeoxycholic Acid

CAS: 128-13-2

Ursodeoxycholic Acid

Purity: 98%

Molecular weight: 392.57g/mol

Ref: 54-OR1029332

Ursodeoxycholic acid

CAS: 128-13-2

Formula: C₂₄H₄₀O₄

Purity: 99.0 - 101.0 % (dried basis)

Color and Shape: White or almost white powder

Molecular weight: 392.56

Ref: 7W-GP1000

Ursodeoxycholic acid

CAS: 128-13-2

Ursodeoxycholic acid

Purity: ≥95%

Molecular weight: 392.57g/mol

Ref: 54-BUP18898

Ursodeoxycholic acid

CAS: 128-13-2

Formula: C₂₄H₄₀O₄

Purity: 95%~99%

Molecular weight: 392.58

Ref: BP-SBP03888

Ursodeoxycholic Acid

CAS: 128-13-2

Color and Shape: White To Off-White

Ref: 86-MM0836.00

Ursodeoxycholic Acid

CAS: 128-13-2

Applications Used as an anticholelithogenic. Epimer with Chenodiol with respect to the hydroxyl group at C7.
References Tint, G.S., et al.: Gastroenterology, 91, 1007 (1986), Poupon, R.E, et al.: N. Engl. J. Med., 324, 1548 (1991), MacKenzie, P., et al.: J. Biol. Chem., 283, 36205 (2008),

Formula: C₂₄H₄₀O₄

Color and Shape: White To Off-White

Molecular weight: 392.57

Ref: TR-U850000

Ursodeoxycholic acid

CAS: 128-13-2

Purity: 98.0%

Color and Shape: Solid, White powder

Molecular weight: 392.5799865722656

Ref: 10-F095820

Ursodeoxycholic acid

Controlled Product

CAS: 128-13-2

Ursodeoxycholic acid is a secondary bile acid, which is derived from the metabolism of primary bile acids by intestinal bacteria. It modifies the composition of bile and reduces the absorption of cholesterol in the gastrointestinal tract by decreasing the cholesterol saturation of bile. This leads to a solubilization of cholesterol gallstones, making it an essential therapeutic agent in the management of cholesterol gallstone disease.

Formula: C₂₄H₄₀O₄

Color and Shape: Powder

Molecular weight: 392.57 g/mol

Ref: 3D-FU09676

Ursodeoxycholic acid

Controlled Product

CAS: 128-13-2

Ursodeoxycholic acid is a naturally occurring bile acid, which is synthesized in the liver from cholesterol. It functions primarily to reduce cholesterol absorption in the intestine and dissolve cholesterol gallstones. This mechanism involves changing the composition of bile and reducing the cholesterol saturation in bile, which reduces micellar cholesterol and bile acid pool size, limiting stone formation.

Formula: C₂₄H₄₀O₄

Purity: Min. 98 Area-%

Molecular weight: 392.58 g/mol

Ref: 3D-U-9000

Ursodeoxycholic Acid (UDCS) extrapure, 99%

CAS: 128-13-2

Formula: C₂₄H₄₀O₄

Purity: min. 99.5%

Color and Shape: White to off-white, Crystalline powder, Clear, Colourless to pale yellow

Molecular weight: 392.57

Ref: SR-50178