CAS 128-13-2: Ursodeoxycholic acid

Description:Ursodeoxycholic acid (UDCA), with the CAS number 128-13-2, is a bile acid that is naturally occurring in the body, primarily synthesized from cholesterol. It is characterized by its hydrophilic properties, which make it less toxic than other bile acids. UDCA is known for its ability to promote the solubilization of cholesterol in bile, thereby aiding in the prevention of cholesterol gallstone formation. It has been utilized therapeutically to treat various liver diseases, including primary biliary cholangitis and certain forms of cholestasis. The compound exhibits a unique structure, featuring a hydroxyl group at the 7-position, which contributes to its solubility and biological activity. Additionally, UDCA has anti-inflammatory and immunomodulatory effects, making it beneficial in managing liver-related conditions. Its mechanism of action involves enhancing bile flow and reducing the toxicity of bile acids, which can be particularly advantageous in liver dysfunction. Overall, ursodeoxycholic acid is a significant compound in both clinical and biochemical contexts, reflecting its importance in gastrointestinal health and disease management.

Formula:C₂₄H₄₀O₄

InChI:InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+,20+,22+,23+,24-/m1/s1

InChI key:InChIKey=RUDATBOHQWOJDD-UZVSRGJWSA-N

SMILES:O=C(O)CCC(C)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CCC12C

Synonyms:
(3α,5β,7β)-3,7-Dihydroxycholan-24-oic acid
17β-(1-Methyl-3-carboxypropyl)etiocholane-3α,7β-diol
3α,7β-Dihydroxy-5β-cholan-24-oate
3α,7β-Dihydroxy-5β-cholan-24-oic acid
3α,7β-Dihydroxy-5β-cholanic acid
3α,7β-Dihydroxy-5β-cholanoic acid
3α,7β-Dihydroxycholanic acid
5β-Cholan-24-oic acid, 3α,7β-dihydroxy-
5β-Cholanic acid, 3α,7β-dihydroxy-
7β-Hydroxylithocholic acid
See more synonyms
Acide Ursodesoxycholique
Acido Ursodeoxicolico
Actigall
Adursal
Arsacol
CHOLON-24-OIC ACID, 3,7-DIHYDROXY-(3α, 5β, 7.β)-
Cholit-Ursan
Delursan
Desocol
Desol
Destolit
Deursil
Litursol
Lyeton
Nsc 683769
Paptarom
Solutrat
Udca
Urdes
Urosiol
Ursacol
Ursic acid
Urso
Ursobilin
Ursochol
Ursocholic acid, deoxy-
Ursocol
Ursodamor
Ursodeoxycholic Acid
Ursodeoxycholsaure
Ursodesoxycholic acid
Ursodiol
Ursofalk
Ursogall
Ursolvan
Ursosan
(4R)-4-[(3R,5S,7S,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
(3alpha,5beta,7beta)-3,7-dihydroxycholan-24-oic acid
2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethanol
(4R)-4-[(3R,5S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
(3alpha,5alpha,7beta)-3,7-dihydroxycholan-24-oate
(3alpha,5beta,7beta)-3,7-dihydroxycholan-24-oate
3alpha,7beta-Dihydroxy-6beta-cholan-24-oic acid
(3alpha,5beta,7beta,8xi,9xi,14xi)-3,7-dihydroxycholan-24-oic acid
Cholan-24-oic acid, 3,7-dihydroxy-, (3α,5β,7β)-
(3alpha,5beta,7alpha)-3,7-dihydroxycholan-24-oic acid
3,7-Dihydroxycholan-24-oic acid