CAS 128-53-0

N-Ethylmaleimide

Description:

N-Ethylmaleimide is an organic compound characterized by its maleimide structure, which features a five-membered ring containing a carbonyl group and a nitrogen atom. It is a colorless to pale yellow liquid at room temperature, exhibiting a distinctive odor. This compound is known for its reactivity, particularly in forming covalent bonds with nucleophiles, making it a valuable reagent in organic synthesis and biochemistry. N-Ethylmaleimide is often used in the modification of proteins and peptides, as it can selectively react with thiol groups, facilitating the study of protein structure and function. Additionally, it is utilized in the production of polymers and as a cross-linking agent in various chemical processes. The compound is soluble in organic solvents such as acetone and ethanol but has limited solubility in water. Safety precautions should be taken when handling N-Ethylmaleimide, as it can be irritating to the skin and eyes, and proper storage conditions are necessary to maintain its stability.

Formula: C₆H₇NO₂

InChI: InChI=1/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3

InChI key: InChIKey=HDFGOPSGAURCEO-UHFFFAOYSA-N

SMILES: C(C)N1C(=O)C=CC1=O

Synonyms:

• 1-Ethyl-1H-pyrrole-2,5-dione
• 1-Ethyl-2,5-dihydro-1H-pyrrole-2,5-dione
• Ethylmaleimide
• Maleic acid N-ethylimide
• Maleimide, N-ethyl-
• N-Ethylmaleimid
• N-Ethylmaleimide
• N-etilmaleimida
• NEM
• Nsc 7638
• 1H-Pyrrole-2,5-dione, 1-ethyl-
• N-Ethylmaleimide, (NEM)
• 1-Ethyl-1H-pyrrole-2,5-dione~NEM
• ethvlmaleimide
• 1-ethyl-1h-pyrrole-5-dione
• USAF B-121
• maleicacidn-ethylimide
• N-ETHYLMALEIMIDE SIGMAULTRA
• N-ETHYLMALEIMIDE 99+%
• n-ethvlmaleimide
• n-ethyl-maleimid
• 5-dione,1-ethyl-1H-Pyrrole-2
• N-Ethylmaleimide-D5
• usafb-121

N-Ethylmaleimide

CAS: 128-53-0

Formula: C₆H₇NO₂

Purity: >98.0%(HPLC)(N)

Color and Shape: White powder to crystal

Molecular weight: 125.13

Ref: 3B-E0136

N-Ethylmaleimide, 99+%

CAS: 128-53-0

N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Micha

Formula: C₆H₇NO₂

Purity: 99+%

Color and Shape: White to pale cream, Crystals or powder or crystalline powder and/or chunks

Molecular weight: 125.13

Ref: 02-040526

N-Ethylmaleimide, 98+%

CAS: 128-53-0

Cysteine alkylating agent N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and pe

Formula: C₆H₇NO₂

Purity: 98+%

Color and Shape: White to cream or pale yellow, Crystals or powder or crystalline powder and/or lumps/chunks or fused solid

Molecular weight: 125.13

Ref: 02-L00355

1H-Pyrrole-2,5-dione, 1-ethyl-

CAS: 128-53-0

Formula: C₆H₇NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 125.1253

Ref: IN-DA000XNW

N-Ethylmaleimide

CAS: 128-53-0

N-Ethylmaleimide

Purity: 98%

Molecular weight: 125.13g/mol

Ref: 54-OR1014360

N-Ethylmaleimide

CAS: 128-53-0

N-Ethylmaleimide

Purity: ≥98%

Molecular weight: 125.13g/mol

Ref: 54-BUP17154

N-Ethylmaleimide

CAS: 128-53-0

Formula: C₆H₇NO₂

Purity: (GC) ≥ 98.0%

Color and Shape: White to light-yellow crystalline powder

Molecular weight: 125.13

Ref: 7W-GK7362

N-Ethylmaleimide

CAS: 128-53-0

N-Ethylmaleimide (NEM) is a reagent for alkylation of free sulfhydryl groups, a cysteine protease inhibitor. Cost-effective and quality-assured.

Formula: C₆H₇NO₂

Purity: 99.50%

Color and Shape: White Solid

Molecular weight: 125.13

Ref: TM-T3088

N-Ethyl Maleimide (1M Solution in Acetonitrile)

Controlled Product

CAS: 128-53-0

Formula: C₆H₇NO₂

Color and Shape: Single Solution

Molecular weight: 125.13

Ref: TR-KIT4159

N-Ethyl Maleimide

Controlled Product

CAS: 128-53-0

Applications Reagent for the covalent modification of cysteine residues in proteins.NEM gives a clear solution in ethanol at 50 mg/ml. NEM dissolves in water (>50 mg in 4 ml); however, aqueous solutions are unstable. The rate of hydrolysis is pseudo-first order and significantly dependent on pH.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sheehan, M., et al.: J. Cell Biol., 106, 1 (1988), Vogel, K., et al.: J. Biol. Chem., 275, 2959 (2000), Ramos, C., et al.: Biochem. J., 400, 393 (2006),

Formula: C₆H₇NO₂

Color and Shape: Neat

Molecular weight: 125.13

Ref: TR-E817900

N-Ethyl maleimide

CAS: 128-53-0

N-Ethyl maleimide is a cytosolic calcium chelator that binds to the calcium ions in the cells. It has been shown to inhibit the enzymes of fatty acid synthesis and phospholipase A2, which are involved in lipid metabolism. N-Ethyl maleimide is an irreversible enzyme inhibitor and can be used as a chemical tool for cell sample preparation. The reaction with N-ethyl maleimide leads to a decrease in water permeability of the cell membrane. This chemical also has a high affinity for sulfhydryl groups and can therefore be used as an anti-oxidant or free radical scavenger.

Formula: C₆H₇NO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 125.13 g/mol

Ref: 3D-FE05855

N-Ethylmaleimide

CAS: 128-53-0

Formula: C₆H₇NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 125.127

Ref: 10-F047870

N-Ethylmaleimide ExiPlus, Multi-Compendial, 99%

CAS: 128-53-0

Formula: C₆H₇NO₂

Purity: min. 99%

Color and Shape: White, Crystalline powder, Clear, Colourless

Molecular weight: 125.13

Ref: SR-81176

N-Ethylmaleimide extrapure, 99%

CAS: 128-53-0

Formula: C₆H₇NO₂

Purity: min. 99%

Color and Shape: White to off-white to pale yellow, Crystalline powder / Crystals

Molecular weight: 125.13

Ref: SR-78503