CAS 129-06-6

(±)-Warfarin sodium

Description:

(±)-Warfarin sodium is an anticoagulant medication primarily used to prevent blood clots in various medical conditions, such as atrial fibrillation and deep vein thrombosis. It is a synthetic derivative of coumarin and functions by inhibiting vitamin K epoxide reductase, which is essential for the synthesis of vitamin K-dependent clotting factors. This compound is characterized by its racemic mixture, consisting of both the R and S enantiomers, each exhibiting different pharmacological properties. Warfarin sodium is typically administered orally and is known for its narrow therapeutic index, necessitating careful monitoring of blood coagulation levels, often measured by the International Normalized Ratio (INR). The substance is soluble in water and has a relatively low molecular weight. Its pharmacokinetics involve absorption, metabolism primarily in the liver, and excretion through urine. Due to its potent effects and potential interactions with various medications and dietary factors, patient management requires a comprehensive understanding of its pharmacodynamics and pharmacokinetics.

Formula: C₁₉H₁₆O₄·Na

InChI: InChI=1S/C19H16O4.Na/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22;/h2-10,15,21H,11H2,1H3;

InChI key: InChIKey=FSSPYKRRYDTFQZ-UHFFFAOYSA-N

SMILES: C(CC(C)=O)(C1=C(O)C=2C(OC1=O)=CC=CC2)C3=CC=CC=C3.[Na]

Synonyms:

• 2H-1-Benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)-, sodium salt
• 2H-1-benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)-, sodium salt (1:1)
• 3-(α-Acetonylbenzyl)-4-hydroxycoumarin sodium
• Aldocumar
• Athrombin
• Coumadan Sodico
• Coumadin
• Coumadin sodium
• Coumadine
• Coumafene sodium
• Coumarin, 3-(α-acetonylbenzyl)-4-hydroxy-, sodium salt
• Dimantil
• Farin
• Marevam
• Marevan
• Orfarin
• Panwarfin
• Prothromadin
• Ratsul Soluble
• Simarc 2
• Sodium coumadin
• Sodium warfarin
• Sodium, [[2-oxo-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-4-yl]oxy]-
• Sofarin
• Taro-warfarin
• Tintorane
• UniWarfin
• Varfine
• Waran
• Warfant
• Warfarin Sodium Crystalline Clathrate
• Warfarin Sodium
• Warfarin sodium salt
• Warfarin, sodium deriv.
• Warfarina
• Warfil 5
• Warfilone

Warfarin Sodium (contains Isopropyl Alcohol)

CAS: 129-06-6, 81-81-2

Formula: C₁₉H₁₅NaO₄

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 330.31

Ref: 3B-W0005

WARFARIN SODIUM CRS

CAS: 129-06-6

WARFARIN SODIUM CRS

Formula: C₁₉H₁₅NaO₄

Color and Shape: Amorphous. White. Powder.

Molecular weight: 330.3098

Ref: 41-W0100000

3-(A-ACETONYLBENZYL)-4-HYDROXYCOUMARIN, SODIUM CLAT

CAS: 129-06-6

Formula: C₁₉H₁₅NaO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 330.3098

Ref: IN-DA003I60

Warfarin sodium salt

CAS: 129-06-6

Formula: C₁₉H₁₆NaO₄

Purity: 97.0 - 102.0 % (anhydrous, isopropyl alcohol-free basis)

Color and Shape: White to off-white crystalline powder

Molecular weight: 331.32

Ref: 7W-GP6872

Warfarin sodium

CAS: 129-06-6

Warfarin sodium

Purity: ≥98%

Molecular weight: 330.31g/mol

Ref: 54-BUP14005

(±)-Warfarin Sodium

CAS: 129-06-6

Applications (±)-Warfarin Sodium, an anticoagulant drug product.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Nguyenpho, A., et al.: J. Pharm. Sci., 104, 4232-4240, (2015)

Formula: C₁₉H₁₅O₄·Na

Color and Shape: Neat

Molecular weight: 330.31

Ref: TR-W498505

Warfarin sodium

CAS: 129-06-6

An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.

Formula: C₁₉H₁₅NaO₄

Purity: 99.81% - 99.97%

Color and Shape: White Or Yellowish Powder

Molecular weight: 330.31

Ref: TM-T0815L

3-(α-Acetonylbenzyl)-4-hydroxycoumarin sodium

CAS: 129-06-6

3-(α-Acetonylbenzyl)-4-hydroxycoumarin sodium is an anticoagulant compound, which is a synthetic derivative of coumarin. It is primarily sourced via chemical synthesis in laboratory settings. Its mode of action involves inhibiting the synthesis of vitamin K-dependent clotting factors, specifically factors II, VII, IX, and X. This inhibition impairs blood coagulation, leading to uncontrolled bleeding.

Formula: C₁₉H₁₅NaO₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 330.31 g/mol

Ref: 3D-FA14805