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CAS 129311-55-3

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Ganirelix Acetate

Description:
Ganirelix acetate is a synthetic peptide that functions as a gonadotropin-releasing hormone (GnRH) antagonist. It is primarily used in assisted reproductive technology to prevent premature ovulation during controlled ovarian stimulation. The substance is characterized by its ability to competitively inhibit the action of GnRH at the pituitary gland, leading to a decrease in the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This mechanism helps to control the timing of ovulation, thereby enhancing the effectiveness of fertility treatments. Ganirelix acetate is typically administered via subcutaneous injection and is known for its relatively short half-life, necessitating careful dosing and timing in clinical applications. The compound is generally well-tolerated, though some patients may experience side effects such as injection site reactions or hormonal fluctuations. Its chemical structure includes a specific sequence of amino acids, contributing to its biological activity and specificity in targeting GnRH receptors. Overall, Ganirelix acetate plays a crucial role in reproductive medicine, facilitating better outcomes in fertility treatments.
Formula:C84H121ClN18O17
InChI:InChI=1/C80H113ClN18O13.2C2H4O2/c1-9-84-79(85-10-2)88-39-17-15-27-60(70(104)94-62(42-49(5)6)71(105)93-61(28-16-18-40-89-80(86-11-3)87-12-4)78(112)99-41-21-29-68(99)77(111)90-50(7)69(82)103)92-72(106)63(44-53-32-36-58(102)37-33-53)97-76(110)67(48-100)98-74(108)65(45-54-22-20-38-83-47-54)96-73(107)64(43-52-30-34-57(81)35-31-52)95-75(109)66(91-51(8)101)46-56-25-19-24-55-23-13-14-26-59(55)56;2*1-2(3)4/h13-14,19-20,22-26,30-38,47,49-50,60-68,100,102H,9-12,15-18,21,27-29,39-46,48H2,1-8H3,(H2,82,103)(H,90,111)(H,91,101)(H,92,106)(H,93,105)(H,94,104)(H,95,109)(H,96,107)(H,97,110)(H,98,108)(H2,84,85,88)(H2,86,87,89);2*1H3,(H,3,4)/t50-,60-,61+,62+,63+,64-,65-,66-,67+,68+;;/m1../s1
Synonyms:
  • D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N(sup 6)-((ethylamino)(ethylimino)methyl)-D-lysyl-L-leucyl-N(sup 6)-((ethylamino)(ethylimino)methyl)-L-lysyl-L-prolyl-, diacetate (salt)
  • Ganirelix acetate injection
  • N-Acetyl-3-(2-naphthyl)-D-alanyl-p-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-N(sup 6)-(N,N'-diethylamidino)-D-lysyl-L-leucyl-N(sup 6)-(N,N'-diethylamidino)-L-lysyl-L-prolyl-D-alaninamide diacetate (salt)
  • Unii-56U7906Fqw
  • Ganirelix acetate
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Found 3 products.
  • D-Alaninamide,N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alany…
    Indagoo
    + Info

    D-Alaninamide,N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis(ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis(ethylamino)methylene]-L-lysyl-L-prolyl-, diacetate (salt)

    CAS:
    Formula:C84H121ClN18O17
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1690.4229

    Ref: IN-DA009BZZ

    5mg
    To inquire
    10mg
    To inquire
    1mg
    647.00€
  • Ganirelix acetate
    Biosynth
    + Info

    Ganirelix acetate

    Controlled Product
    CAS:

    Ganirelix acetate is a synthetic, non-steroidal, anti-hormonal agent of the gonadotropin releasing hormone (GnRH) receptor antagonist class. It is used in research as a building block for fine chemical and pharmaceutical synthesis. Ganirelix acetate has been shown to be useful in the synthesis of drugs that target the GnRH receptor or other receptors with high affinity for GnRH. This compound can act as an intermediate in many chemical reactions and is also a versatile scaffold for drug design.

    Formula:C80H113ClN18O13•(C2H4O2)2
    Purity:Min. 95%
    Color and Shape:White Powder
    Molecular weight:1,690.42 g/mol

    Ref: 3D-FG23647

    100mg
    To inquire
    250mg
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    5mg
    207.00€
    10mg
    327.00€
    50mg
    770.00€
  • Ganirelix Trifluoroacetic Acid Salt (>90%)
    TRC
    + Info

    Ganirelix Trifluoroacetic Acid Salt (>90%)

    Controlled Product
    CAS:

    Applications Decapeptide LH-RH antagonist. Used in treatment of infertility.
    References Strickley, R.G., et al.: Pharm. Res., 7, 530 (1990), Jung, G., et al.: J. Med. Chem., 35, 3942 (1992), Rabinovici, J., et al.: J. Clin. Endocrinol. Metab., 75, 1220 (1992), Devroey, P., et al.: Hum. Reprod., 13, 3023 (1998),

    Formula:C80H113ClN18O13•x(C2HF3O2)
    Purity:>90%
    Color and Shape:Neat
    Molecular weight:1570.3211402

    Ref: TR-G245000

    1mg
    226.00€
    5mg
    793.00€
    10mg
    1,232.00€