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CAS 129318-43-0

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Alendronate sodium

Description:
Alendronate sodium is a bisphosphonate medication primarily used to treat osteoporosis and other conditions that lead to bone loss. It functions by inhibiting osteoclast-mediated bone resorption, thereby increasing bone mineral density. The substance is typically administered orally and is characterized by its high solubility in water, which facilitates its absorption in the gastrointestinal tract. Alendronate sodium is a white to off-white crystalline powder, and it is stable under normal conditions but sensitive to moisture and light. Its molecular structure includes a phosphonate group, which is essential for its biological activity. The compound is often formulated as a sodium salt to enhance its stability and solubility. Common side effects may include gastrointestinal discomfort, and it is generally recommended to be taken on an empty stomach to maximize absorption. Due to its mechanism of action, alendronate sodium is also studied for potential applications in other metabolic bone diseases. Proper administration and adherence to guidelines are crucial for its effectiveness and to minimize adverse effects.
Formula:C4H13NO7P2·Na
InChI:InChI=1S/C4H13NO7P2.Na/c5-3-1-2-4(6,13(7,8)9)14(10,11)12;/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12);
InChI key:InChIKey=NLILQNGSPQHASV-UHFFFAOYSA-N
SMILES:C(P(=O)(O)O)(P(=O)(O)O)(CCCN)O.[Na]
Synonyms:
  • (4-Amino-1-hydroxybutylidene) bisphosphonic acid monosodium salt
  • 4-Amino-1-Hydroxy-1-Phosphonobutyl Phosphonic Acid, Monosodium
  • 4-Amino-1-hydroxy-1,1-butanediphosphonic acid monosodium salt
  • 4-Amino-1-hydroxybutylidene-1,1-bisphosphonic acid monosodium salt
  • Alend
  • Alendronate
  • Alendronic acid monosodium salt
  • Alenmax
  • Bifosa
  • Bonalon
  • See more synonyms
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