![Estra-1,3,5(10)-triene-3,17-diol, 7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]-, (7α,17β)-](https://static.cymitquimica.com/cas-image/thumb-webp/339688-fulvestrant.webp)
CAS 129453-61-8
:Estra-1,3,5(10)-triene-3,17-diol, 7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]-, (7α,17β)-
Description:
Estra-1,3,5(10)-triene-3,17-diol, 7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]-, (7α,17β)-, identified by CAS number 129453-61-8, is a synthetic compound that belongs to the class of steroid hormones, specifically a derivative of estradiol. This compound features a complex structure characterized by a steroid backbone with multiple functional groups, including hydroxyl (-OH) groups and a sulfinyl group attached to a long alkyl chain. The presence of the pentafluoropentyl group enhances its lipophilicity, potentially affecting its biological activity and interaction with cellular membranes. The stereochemistry indicated by (7α,17β) suggests specific spatial arrangements of atoms that can influence the compound's pharmacological properties. Such compounds are often studied for their potential applications in hormone replacement therapy, contraceptives, or as research tools in endocrinology. However, detailed studies on its biological effects, pharmacokinetics, and toxicity would be necessary to fully understand its characteristics and potential uses.
Formula:C32H47F5O3S
InChI:InChI=1/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22?,26-,27+,28+,29-,30+,41?/m1/s1
InChI key:InChIKey=VWUXBMIQPBEWFH-WCCTWKNTSA-N
SMILES:C(CCCCCCCCS(CCCC(C(F)(F)F)(F)F)=O)[C@H]1[C@@]2([C@@](C=3C(C1)=CC(O)=CC3)(CC[C@@]4(C)[C@]2(CC[C@@H]4O)[H])[H])[H]
Synonyms:- Fulvestrant
- Faslodex
- (17beta)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1,3,5(10)-triene-3,17-diol
- ICI 182780
- (7alpha,17beta)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1,3,5(10)-triene-3,17-diol
- Estra-1,3,5(10)-triene-3,17-diol, 7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]-, (7α,17β)-
- ZD 182780
- (7α,17β)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol
- (7a,17b)-7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol
- 7A,17B-[9[(4,4,5,5,5-PENTAFLUOROPENTYL)SULFINYL]NONYL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL
- (7alpha,17beta)-nonyl)
- (717b)-7-[9-[4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol
- zm182780
- estra-1,3,5(10)-triene-3,17-diol,7-(9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)
- (7,17)-7-[9-[4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol
- Faslodex, ICI 182,780, ZD 182780, ZD 9238, ZM 182780, (7a,17b)-7-[9-[(4,4,5,5,5pentafluoropentyl)Sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol
- zd182780
- ICI-187280
- Fulvstrant
- FULVESTRANT-13C1-D2
- 7α-[9-[(4,4,5,5,5,-Pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17β-diol
- See more synonyms
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Fulvestrant
CAS:Formula:C32H47F5O3SPurity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:606.78Fulvestrant
CAS:Estrogens and progestinsFormula:C32H47F5O3SColor and Shape:White PowderMolecular weight:606.31661Fulvestrant-d3
CAS:Formula:C32H44D3F5O3SColor and Shape:White To Off-White SolidMolecular weight:609.80Fulvestrant
CAS:Formula:C32H47F5O3SPurity:(HPLC) ≥ 98.0%Color and Shape:White to off-white powderMolecular weight:606.77Fulvestrant
CAS:Fulvestrant (ZM 182780) is an estrogen receptor (ER) antagonist (IC50=9.4 nM) and an agonist of GPR30.Formula:C32H47F5O3SPurity:99.1% - >99.99%Color and Shape:White PowderMolecular weight:606.77Fulvestrant-d3
CAS:Controlled ProductFormula:C32H44D3F5O3SColor and Shape:NeatMolecular weight:609.79Fulvestrant - Bio-X ™
CAS:Controlled ProductFulvestrant is an estrogen receptor antagonist that is used in the treatment of HR+ breast cancer. This drug can be used as monotherapy or in combination with Alpelisib. Fulvestrant works both by down-regulating and by degrading the estrogen receptor.Formula:C32H47F5O3SPurity:Min. 95%Color and Shape:PowderMolecular weight:606.77 g/molFulvestrant
CAS:Controlled ProductEstrogen receptor antagonistFormula:C32H47F5O3SPurity:Min. 99.0 Area-%Color and Shape:White PowderMolecular weight:606.77 g/molFulvestrant-d4
CAS:Controlled ProductFormula:C32D4H43F5O3SColor and Shape:NeatMolecular weight:610.7959,11-Dehydro Fulvestrant
CAS:Controlled ProductFormula:C32H45F5O3SColor and Shape:NeatMolecular weight:604.755
