CAS 129497-78-5

Verteporfin

Description:

Verteporfin is a photosensitizing agent primarily used in photodynamic therapy, particularly for the treatment of age-related macular degeneration and certain types of cancer. It is a dark green to black powder that is soluble in organic solvents but has limited solubility in water. The compound is characterized by its ability to produce reactive oxygen species upon activation by light, which leads to localized tissue destruction in targeted areas. Verteporfin has a molecular formula that includes carbon, hydrogen, nitrogen, and oxygen, reflecting its complex structure. Its mechanism of action involves the absorption of specific wavelengths of light, which triggers a photochemical reaction that damages cellular components, ultimately leading to cell death. Due to its photosensitivity, patients treated with verteporfin are advised to avoid direct sunlight for a period following treatment to prevent skin reactions. Overall, verteporfin is a significant compound in the field of medical therapeutics, particularly in oncology and ophthalmology.

Formula: C₄₁H₄₂N₄O₈

Synonyms:

• Verteporfin
• 23H,25H-Benzo[b]porphine-9,13-dipropanoic acid, 18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-, monomethyl ester, trans-
• BPD-MA
• 24H,26H-Benzo[b]porphine-9,13-dipropanoic acid, 18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-, monomethyl ester, (4R,4aS)-rel-
• CL 318952

Verteporfin

CAS: 129497-78-5

Drugs with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoi

Formula: C₄₁H₄₂N₄O₈

Color and Shape: Black Dark Green Powder

Molecular weight: 718.30026

Ref: 45-1711461

24H,26H-Benzo[b]porphine-9,13-dipropanoic acid, 18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-, monomethyl ester, (4R,4aS)-rel-

CAS: 129497-78-5

Formula: C₄₁H₄₂N₄O₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 718.7942

Ref: IN-DA000Z64

Verteporfin

CAS: 129497-78-5

Verteporfin

Purity: ≥95%

Molecular weight: 718.79g/mol

Ref: 54-BUP12383

Verteporfin

CAS: 129497-78-5

Color and Shape: Neat

Ref: 86-MM3890.00

Verteporfin

CAS: 129497-78-5

Verteporfin (BPD-MA) is a YAP inhibitor that inhibits YAP-TEAD interactions.

Formula: C₄₁H₄₂N₄O₈

Purity: 95.37% - 99.82%

Color and Shape: Dark Green To Black Solid

Molecular weight: 718.79

Ref: TM-T3112

Verteporfin

CAS: 129497-78-5

Formula: C₄₁H₄₂N₄O₈

Molecular weight: 718.81

Ref: 4Z-V-061001

Verteporfin

Controlled Product

CAS: 129497-78-5

Applications Verteporfin is a photosensitizer that is used in photodynamic therapy (PDT). Verteporfin can accumulate in tumor tissues allowing for 30 to 150 minutes optimal PDT after intravenous administration.
References Levy, J.G.: Semin. Oncol., 21, 4 (1994)

Formula: C₄₁H₄₂N₄O₈

Color and Shape: Dark Green

Molecular weight: 1437.59

Ref: TR-V128800

Verteporfin - mixture of isomer

CAS: 129497-78-5

Verteporfin is a drug that is used in the treatment of age-related macular degeneration. It is an organic compound that has two isomers, namely (S)- and (R)-verteporfin. The drug is injected intravenously and causes temporary damage to the choroid, which allows new blood vessels to grow. Verteporfin may also be used as an adjunct to photodynamic therapy for the treatment of choroidal neovascularization and occlusion. Verteporfin may be administered in combination with other drugs such as benzoporphyrin derivative for the treatment of age-related macular degeneration during phase I/II clinical trials.

Formula: C₄₁H₄₂N₄O₈

Purity: Min. 95%

Color and Shape: Dark Green To Black Solid

Molecular weight: 718.79 g/mol

Ref: 3D-FV171702