CAS 129722-12-9
:Aripiprazole
Description:
Aripiprazole is an atypical antipsychotic medication primarily used to treat schizophrenia, bipolar disorder, and as an adjunct in major depressive disorder. It functions as a partial agonist at dopamine D2 receptors and serotonin 5-HT1A receptors, while also acting as an antagonist at 5-HT2A receptors, which contributes to its unique pharmacological profile. This mechanism helps to stabilize mood and reduce psychotic symptoms. Aripiprazole is characterized by its relatively low sedative effects compared to other antipsychotics, making it a preferred option for some patients. The substance is typically administered orally, but can also be given via intramuscular injection. Its chemical structure includes a quinolinone core, which is essential for its activity. Aripiprazole is generally well-tolerated, though it may cause side effects such as akathisia, weight gain, and metabolic changes in some individuals. As with any medication, it is important for patients to be monitored for efficacy and adverse effects during treatment.
Formula:C23H27Cl2N3O2
InChI:InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)
InChI key:InChIKey=CEUORZQYGODEFX-UHFFFAOYSA-N
SMILES:O(CCCCN1CCN(CC1)C2=C(Cl)C(Cl)=CC=C2)C=3C=C4C(=CC3)CCC(=O)N4
Synonyms:- 2(1H)-Quinolinone, 7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-
- 7-[4-[4-(2,3-Dichlorophenyl)-1-Piperazinyl]Butoxy]-3,4-Dihydrocarbostyril
- 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone
- 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one
- Abilify
- Abilitat
- Aripiperazole
- Aripiprazol
- Aripiprizole
- Aripirazole
- Aristab
- Arpizol
- Asprito
- Biopiprazole
- Opc 14597
- Opc 31
- Pripiprazole
- Aripiprazole
- OPC 31-d8-
- ARIPIPRAZOLE-D8
- OPC-14597, OPC-31,
- Abilify-d8
- Abilitat-d8
- Alipiprazole
- 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl-d8]butoxy]-3,4-dihydro-2(1H)-quinolinone
- 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl-d8]butoxy]-3,4-dihydrocarbostyril
- 7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
- OPC 14597-d8
- See more synonyms
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Aripiprazole
CAS:Formula:C23H27Cl2N3O2Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:448.39Aripiprazole
CAS:AripiprazoleFormula:C23H27Cl2N3O2Purity:98.8%Color and Shape:Off-WhiteMolecular weight:447.14803ARIPIPRAZOLE CRS
CAS:ARIPIPRAZOLE CRSFormula:C23H27Cl2N3O2Color and Shape:White. Whitish. Crystalline Powder.Molecular weight:448.3854Aripiprazole
CAS:Lactams, nesoiFormula:C23H27Cl2N3O2Color and Shape:White Pale Yellow PowderMolecular weight:447.14803Aripiprazole
CAS:Aripiprazole (OPC-14597) is a piperazine/quinolone antipsychotic, partial agonist at 5-HT1A/D2, and antagonist at 5-HT2A.Formula:C23H27Cl2N3O2Purity:99.43% - 99.62%Color and Shape:White SolidMolecular weight:448.39Aripiprazole
CAS:AripiprazoleFormula:C23H27Cl2N3O2Purity:99%Color and Shape:SolidMolecular weight:448.39Aripiprazole
CAS:Formula:C23H27Cl2N3O2Purity:≥ 98.0%Color and Shape:White to off-white powderMolecular weight:448.39Aripiprazole
CAS:Formula:C23H27Cl2N3O2Color and Shape:White To Off-White SolidMolecular weight:448.39Aripiprazole (Standard)
CAS:Aripiprazole (Standard) is a reference standard for research and analysis in studies involving Aripiprazole. Aripiprazole (OPC-14597) is an antipsychotic agent that is structurally related to piperazines and quinolones. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a post-synaptic antagonist, and an antagonist of SEROTONIN RECEPTOR, 5-HT2A.Formula:C23H27Cl2N3O2Color and Shape:SolidMolecular weight:448.39Aripiprazole
CAS:Controlled ProductApplications Aripiprazole is an agonist at the dopamine autoreceptor and an antagonist at the postsynaptic D2 receptor (1,2,3,4). Aripiprazole is an antipsychotic and a potential drug candidate for treating psychoses such as schizophrenia.
References (1) Canive, J.M., et al.: Psychopharmacol. Bull., 34, 101 (1998)(2) Shiokawa, M., et al.: Eur.J.Pharmacol. 570, 108 (2007)(3) Oshiro, Y., et al.: J. Med. Chem. 41, 658 (1998)(4) Ozdemir, V., et al.: Curr Opin Investig Drugs. 3, 113 (2002)Formula:C23H27Cl2N3O2Color and Shape:NeatMolecular weight:448.39Aripiprazole - Bio-X ™
CAS:Controlled ProductAripiprazole is an antipsychotic drug that is used in the treatment for various mood and psychotic disorders such as schizophrenia, depression and bipolar disorder. Although, its mechanism is not fully understood, the antipsychotic action of aripiprazole is likely due to its partial agonist activity on D2 and 5-HT1A receptors as well as its antagonist activity at 5-HT2A receptors.
Formula:C23H27Cl2N3O2Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:448.38 g/molAripiprazole
CAS:Controlled ProductPartial agonist of dopamine (D2) and serotonin (5-HT1A) receptorsFormula:C23H27Cl2N3O2Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:448.38 g/mol
