CAS 129722-12-9

Aripiprazole

Description:

Aripiprazole is an atypical antipsychotic medication primarily used to treat schizophrenia, bipolar disorder, and as an adjunct in major depressive disorder. It functions as a partial agonist at dopamine D2 receptors and serotonin 5-HT1A receptors, while also acting as an antagonist at 5-HT2A receptors, which contributes to its unique pharmacological profile. This mechanism helps to stabilize mood and reduce psychotic symptoms. Aripiprazole is characterized by its relatively low sedative effects compared to other antipsychotics, making it a preferred option for some patients. The substance is typically administered orally, but can also be given via intramuscular injection. Its chemical structure includes a quinolinone core, which is essential for its activity. Aripiprazole is generally well-tolerated, though it may cause side effects such as akathisia, weight gain, and metabolic changes in some individuals. As with any medication, it is important for patients to be monitored for efficacy and adverse effects during treatment.

Formula: C₂₃H₂₇Cl₂N₃O₂

InChI: InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)

InChI key: InChIKey=CEUORZQYGODEFX-UHFFFAOYSA-N

SMILES: O(CCCCN1CCN(CC1)C2=C(Cl)C(Cl)=CC=C2)C=3C=C4C(=CC3)CCC(=O)N4

Synonyms:

• 2(1H)-Quinolinone, 7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-
• 7-[4-[4-(2,3-Dichlorophenyl)-1-Piperazinyl]Butoxy]-3,4-Dihydrocarbostyril
• 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone
• 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one
• Abilify
• Abilitat
• Aripiperazole
• Aripiprazol
• Aripiprizole
• Aripirazole
• Aristab
• Arpizol
• Asprito
• Biopiprazole
• Opc 14597
• Opc 31
• Pripiprazole
• Aripiprazole
• OPC 31-d8-
• ARIPIPRAZOLE-D8
• OPC-14597, OPC-31,
• Abilify-d8
• Abilitat-d8
• Alipiprazole
• 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl-d8]butoxy]-3,4-dihydro-2(1H)-quinolinone
• 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl-d8]butoxy]-3,4-dihydrocarbostyril
• 7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
• OPC 14597-d8

Aripiprazole

Controlled Product

CAS: 129722-12-9

Partial agonist of dopamine (D2) and serotonin (5-HT1A) receptors

Formula: C₂₃H₂₇Cl₂N₃O₂

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 448.38 g/mol

Ref: 3D-FA17978