CAS 130143-01-0

Cetrorelix diacetate

Description:

Cetrorelix diacetate is a synthetic peptide and a potent gonadotropin-releasing hormone (GnRH) antagonist, primarily used in the field of reproductive medicine. It is characterized by its ability to inhibit the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by blocking the GnRH receptors in the pituitary gland. This action is particularly beneficial in controlled ovarian hyperstimulation protocols for assisted reproductive technologies, as it helps prevent premature ovulation. The diacetate form indicates that the compound has two acetate groups, which can influence its solubility and stability. Cetrorelix diacetate is typically administered via subcutaneous injection and is known for its relatively short half-life, necessitating careful dosing in clinical settings. The compound is generally well-tolerated, with side effects that may include injection site reactions and hormonal fluctuations. Its chemical structure includes a sequence of amino acids, contributing to its biological activity and specificity in targeting GnRH receptors.

Formula: C₇₂H₉₆ClN₁₇O₁₆

InChI: InChI=1/C70H92ClN17O14.C2H4O2/c1-39(2)31-52(61(94)82-51(15-9-28-77-69(73)74)68(101)88-30-10-16-58(88)67(100)79-40(3)59(72)92)83-60(93)50(14-8-29-78-70(75)102)81-63(96)54(34-43-20-25-49(91)26-21-43)86-66(99)57(38-89)87-65(98)56(36-45-11-7-27-76-37-45)85-64(97)55(33-42-18-23-48(71)24-19-42)84-62(95)53(80-41(4)90)35-44-17-22-46-12-5-6-13-47(46)32-44;1-2(3)4/h5-7,11-13,17-27,32,37,39-40,50-58,89,91H,8-10,14-16,28-31,33-36,38H2,1-4H3,(H2,72,92)(H,79,100)(H,80,90)(H,81,96)(H,82,94)(H,83,93)(H,84,95)(H,85,97)(H,86,99)(H,87,98)(H4,73,74,77)(H3,75,78,102);1H3,(H,3,4)/t40-,50-,51+,52+,53-,54+,55-,56-,57+,58+;/m1./s1

InChI key: DTPVYWHLQLAXFT-SMCUOGPFSA-N

SMILES: C[C@H](C(=O)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CCCNC(=O)N)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CO)NC(=O)[C@@H](CC3=CN=CC=C3)NC(=O)[C@@H](CC4=CC=C(C=C4)Cl)NC(=O)[C@@H](CC5=CC6=CC=CC=C6C=C5)NC(=O)C.CC(=O)O.CC(=O)O

Synonyms:

• N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide diacetate

Cetrorelix diacetate

CAS: 130143-01-0

Cetrorelix diacetate

Formula: C₇₄H₁₀₀ClN₁₇O₁₈

Purity: ≥98%

Molecular weight: 1551.17

Ref: 54-BUP09136

Cetrorelix diacetate

CAS: 130143-01-0

Formula: C₇₄H₁₀₀ClN₁₇O₁₈

Purity: 98.38%

Molecular weight: 1551.1419

Ref: IN-DA01DQ1P

Cetrorelix diacetate

CAS: 130143-01-0

Cetrorelix diacetate (NS-75A) is is a gonadotropin-releasing hormone antagonist.

Formula: C₇₄H₁₀₀ClN₁₇O₁₈

Purity: 98.38%

Color and Shape: White Solid

Molecular weight: 1551.142

Ref: TM-T5520L

Cetrorelix acetate

CAS: 130143-01-0

Synthetic antagonist of GnRH receptor

Formula: C₇₀H₉₂ClN₁₇O₁₄

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 1429.66982

Ref: 3D-FC61440

Cetrorelix Diacetate

CAS: 130143-01-0

Formula: C₇₀H₉₂ClN₁₇O₁₄C₂H₄O₂

Molecular weight: 1431.06 : 2(60.05)

Ref: ST-EA-CP-C267030