CAS 130209-82-4: Latanoprost
Description:Latanoprost is a synthetic prostaglandin analog primarily used in the treatment of glaucoma and ocular hypertension. It functions by increasing the outflow of aqueous humor, thereby reducing intraocular pressure. The substance is characterized by its ability to selectively bind to the prostaglandin F2α receptor, which plays a crucial role in its mechanism of action. Latanoprost is typically administered as an ophthalmic solution, and its formulation often includes preservatives to enhance stability and shelf life. The compound is known for its relatively high lipophilicity, allowing it to penetrate ocular tissues effectively. Common side effects may include eye redness, changes in iris pigmentation, and eyelash growth. Latanoprost is generally well-tolerated, but it is contraindicated in patients with a history of hypersensitivity to the drug or its components. Its pharmacokinetics involve rapid absorption and metabolism, with a half-life that supports once-daily dosing, making it a convenient option for patients managing chronic eye conditions.
Formula:C26H40O5
InChI:InChI=1S/C26H40O5/c1-19(2)31-26(30)13-9-4-3-8-12-22-23(25(29)18-24(22)28)17-16-21(27)15-14-20-10-6-5-7-11-20/h3,5-8,10-11,19,21-25,27-29H,4,9,12-18H2,1-2H3/b8-3-/t21-,22+,23+,24-,25+/m0/s1
InChI key:InChIKey=GGXICVAJURFBLW-CEYXHVGTSA-N
SMILES:O=C(OC(C)C)CCCC=CCC1C(O)CC(O)C1CCC(O)CCC=2C=CC=CC2
- Synonyms:
- 5-Heptenoic acid, 7-[3,5-dihydroxy-2-(3-hydroxy-5-phenylpentyl)cyclopentyl]-, 1-methylethyl ester, [1R-[1α(Z),2β(R*),3α,5α]]-
- PhXA 41
- XA 41
- Latanoprost
- 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-, 1-methylethyl ester, (5Z)-