CAS 1304701-57-2

Formula: C24H30ClN7O4S

InChI: InChI=1S/C24H30ClN7O4S/c1-31(2)24(36)13-4-6-15(27-20(33)21(34)30-19-7-5-14(25)11-26-19)17(10-13)28-22(35)23-29-16-8-9-32(3)12-18(16)37-23/h5,7,11,13,15,17H,4,6,8-10,12H2,1-3H3,(H,27,33)(H,28,35)(H,26,30,34)/t13-,15-,17+/m0/s1/i1D3,2D3

InChI key: HGVDHZBSSITLCT-KUPMTGFDSA-N

SMILES: [2H]C([2H])([2H])N(C(=O)[C@H]1CC[C@@H]([C@@H](C1)NC(=O)C2=NC3=C(S2)CN(CC3)C)NC(=O)C(=O)NC4=NC=C(C=C4)Cl)C([2H])([2H])[2H]

Edoxaban-d6

CAS: 1304701-57-2

Edoxaban-d6

Formula: C₂₄H₂₄ClD₆N₇O₄S

Purity: 99%

Molecular weight: 554.09

Ref: 54-DE3189

Edoxaban-d6

CAS: 1304701-57-2

Formula: C₂₄H₂₄D₆ClN₇O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 554.10

Ref: 4Z-E-080002

Edoxaban-d6

Controlled Product

CAS: 1304701-57-2

Stability Hygroscopic
Applications Edoxaban-d6 is the isotope labelled analog of Edoxaban (E555520); an anticoagulant drug which acts as a direct factor Xa inhibitor.
References Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010)

Formula: C₂₄H₂₄D₆ClN₇O₄S

Color and Shape: Neat

Molecular weight: 554.09

Ref: TR-E555522

Edoxaban-d6

CAS: 1304701-57-2

Formula: C₂₄H₂₄D₆ClN₇O₄S

Molecular weight: 554.1

Ref: ST-EA-CP-IL0199

Edoxaban-d6

CAS: 1304701-57-2

Formula: C₂₄H₃₀ClN₇O₄S

Molecular weight: 554.1

Ref: BE-RMCE014002

Edoxaban-[d6]

CAS: 1304701-57-2

Formula: C₂₄H₃₀ClN₇O₄S

Molecular weight: 554.1

Ref: BE-MD-7475

Edoxaban-D6

CAS: 1304701-57-2

Edoxaban-D6 is a deuterated compound of Edoxaban. Edoxaban (T2368L) has a CAS number of 480449-70-5. Edoxaban (DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.

Formula: C₂₄H₂₄D₆ClN₇O₄S

Color and Shape: Solid

Molecular weight: 554.09

Ref: TM-TMIJ-0132

Edoxaban-d6

CAS: 1304701-57-2

Edoxaban-d6 is a nonsteroidal anti-inflammatory drug that belongs to the group of platelet aggregation inhibitors. It is used to prevent blood clots and stroke in patients with atrial fibrillation. Edoxaban-d6 is a prodrug that needs to be converted into its active form by esterases in the body before it can act. This conversion process involves hydrolysis of the ester moiety and opening of the lactam ring. The metabolism of edoxaban-d6 has been shown to be age dependent, with older subjects having lower levels of esterase activity than younger subjects.

Formula: C₂₄H₃₀ClN₇O₄S

Purity: Min. 95%

Molecular weight: 554.1 g/mol

Ref: 3D-ECC70157