CAS 13075-38-2

N-cbz-gly-pro-gly-gly-pro-ala

Description:

N-Cbz-gly-pro-gly-gly-pro-ala, with the CAS number 13075-38-2, is a synthetic peptide that consists of a sequence of amino acids, specifically glycine (Gly), proline (Pro), and alanine (Ala), with a carbobenzyloxy (Cbz) protecting group on the N-terminus. This compound is characterized by its peptide bond formation, which links the amino acids together, contributing to its structural and functional properties. The presence of proline in the sequence introduces unique conformational characteristics due to its cyclic structure, which can influence the peptide's overall stability and folding. The Cbz group serves as a protective moiety, often used in peptide synthesis to prevent unwanted reactions at the amino group. N-Cbz-gly-pro-gly-gly-pro-ala may have applications in biochemical research, particularly in studies involving peptide synthesis, protein interactions, and drug development. Its properties, such as solubility and reactivity, can vary depending on the specific conditions and the presence of other chemical entities.

Formula: C₂₇H₃₆N₆O₉

InChI: InChI=1/C27H36N6O9/c1-17(26(39)40)31-25(38)20-10-6-12-33(20)22(35)14-28-21(34)13-29-24(37)19-9-5-11-32(19)23(36)15-30-27(41)42-16-18-7-3-2-4-8-18/h2-4,7-8,17,19-20H,5-6,9-16H2,1H3,(H,28,34)(H,29,37)(H,30,41)(H,31,38)(H,39,40)/t17-,19-,20-/m0/s1

SMILES: C[C@@H](C(=O)O)N=C([C@@H]1CCCN1C(=O)CN=C(CN=C([C@@H]1CCCN1C(=O)CN=C(O)OCc1ccccc1)O)O)O

Synonyms:

• Z-Gly-Pro-Gly-Gly-Pro-Ala-OH
• N-[(benzyloxy)carbonyl]glycyl-L-prolylglycylglycyl-L-prolyl-L-alanine

Z-Gly-Pro-Gly-Gly-Pro-Ala-OH

CAS: 13075-38-2

Substrate for microbial collagenase (MMP-1). Enzymatic cleavage of Z-GPGGPA yields Gly-Pro-Ala, which is determined colorimetrically by reaction with ninhydrin. Z-GPGGPA can induce metamorphosis in larvae and asexual buds of the Cassiopea species of jellyfish in vitro at micromolar concentration.

Formula: C₂₇H₃₆N₆O₉

Purity: 98.7%

Color and Shape: White Powder

Molecular weight: 588.62

Ref: 01-4002149

L-Alanine, N-[(phenylmethoxy)carbonyl]glycyl-L-prolylglycylglycyl-L-prolyl-

CAS: 13075-38-2

Formula: C₂₇H₃₆N₆O₉

Molecular weight: 588.6095

Ref: IN-DA000UX0

Z-Gly-Pro-Gly-Gly-Pro-Ala-OH

CAS: 13075-38-2

Z-Gly-Pro-Gly-Gly-Pro-Ala-OH is a synthetic substrate. It is used in tissue culture to measure collagenase activity, as well as in skin cells to measure the activity of v. anguillarum. The optimum pH for this substrate is 5.5 and it has been shown to be stable in high salt environments. This substrate also reacts with human liver granulosa cells and has been shown to have neutral pH properties. Z-Gly-Pro-Gly-Gly-Pro-Ala-OH is an enzyme substrate that is involved in many different enzyme activities including protein synthesis and hydrogen bonding.

Formula: C₂₇H₃₆N₆O₉

Purity: Min. 95%

Molecular weight: 588.61 g/mol

Ref: 3D-FG110841