CAS 1307896-46-3

Formula: C24H26N4O5

InChI: InChI=1S/C24H26N4O5/c1-24(2,13-29)26-23(30)16(12-25)8-14-6-7-18-17(9-14)21(28-27-18)15-10-19(31-3)22(33-5)20(11-15)32-4/h6-11,29H,13H2,1-5H3,(H,26,30)(H,27,28)/b16-8+

InChI key: FCCMYBKAZCDQGX-LZYBPNLTSA-N

SMILES: CC(C)(CO)NC(=O)/C(=C/C1=CC2=C(C=C1)NN=C2C3=CC(=C(C(=C3)OC)OC)OC)/C#N

RMM-46

CAS: 1307896-46-3

RMM-46

Formula: C₂₄H₂₆N₄O₅

Purity: 98%

Molecular weight: 450.49

Ref: 54-BUP17945

RMM-46

CAS: 1307896-46-3

RMM-46 is a reversible covalent inhibitor with high ligand efficiency and selectivity for MSK/RSK family kinases.

Formula: C₂₄H₂₆N₄O₅

Purity: 98.15%

Color and Shape: Yellow Solid

Molecular weight: 450.49

Ref: TM-T26103

RMM 46

CAS: 1307896-46-3

RMM 46 is a chemoproteomic inhibitor that selectively inhibits protein synthesis by reversibly covalently binding to the eukaryotic translation initiation factor 2A (eIF2A). This inhibitor has been shown to be non-catalytic and reversible, which means that it does not inhibit other protein kinases. The irreversible inhibition of the eIF2A by RMM 46 has been shown to result in a decrease in protein synthesis and a number of physiological effects including decreased granule size. RMM 46 has also been shown to have selectivity for the eIF2A over other protein kinases.

Formula: C₂₄H₂₆N₄O₅

Purity: Min. 95%

Molecular weight: 450.5 g/mol

Ref: 3D-HCC89646