CymitQuimica logo

CAS 130929-57-6

:

Entacapone

Description:
Entacapone is a chemical compound primarily used as a medication in the treatment of Parkinson's disease. It functions as a selective and reversible inhibitor of catechol-O-methyltransferase (COMT), an enzyme that metabolizes levodopa, thereby enhancing the effectiveness of levodopa therapy. The molecular formula of entacapone is C14H15N3O5, and it has a molecular weight of approximately 289.29 g/mol. The compound appears as a yellow to orange crystalline powder and is typically administered orally. Entacapone is known for its ability to prolong the action of levodopa by preventing its breakdown, which helps to manage motor symptoms associated with Parkinson's disease. It is often used in combination with other medications, such as carbidopa and levodopa, to improve patient outcomes. The substance is generally well-tolerated, although it may cause side effects such as gastrointestinal disturbances and dyskinesia. As with any medication, it is important for patients to consult healthcare professionals regarding its use and potential interactions with other drugs.
Formula:C14H15N3O5
InChI:InChI=1S/C14H15N3O5/c1-3-16(4-2)14(20)10(8-15)5-9-6-11(17(21)22)13(19)12(18)7-9/h5-7,18-19H,3-4H2,1-2H3/b10-5+
InChI key:InChIKey=JRURYQJSLYLRLN-BJMVGYQFSA-N
SMILES:C(=C(/C(N(CC)CC)=O)\C#N)\C1=CC(N(=O)=O)=C(O)C(O)=C1
Synonyms:
  • (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide
  • (2E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide
  • (E)-Entacapone
  • 2-Cyano-3-(5-Dihydroxyamino-3,4-Dioxo-1-Cyclohexa-1,5-Dienyl)-N,N-Diethyl-Prop-2-Enamide
  • 2-Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-, (2E)-
  • 2-Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-, (E)-
  • Comtan
  • Comtess
  • Entacom
  • Or 611
  • See more synonyms
Found 20 products.