CAS 1313725-88-0

1-[(1S)-1-Imidazo[1,2-a]pyridin-6-ylethyl]-6-(1-methyl-1H-pyrazol-4-yl)-1H-1,2,3-triazolo[4,5-b]pyrazine

Description:

1-[(1S)-1-Imidazo[1,2-a]pyridin-6-ylethyl]-6-(1-methyl-1H-pyrazol-4-yl)-1H-1,2,3-triazolo[4,5-b]pyrazine is a complex organic compound characterized by its multi-ring structure, which includes imidazole, pyrazole, and triazole moieties. This compound features a chiral center, contributing to its stereochemistry, which can influence its biological activity and interactions. It is typically synthesized through multi-step organic reactions, often involving coupling reactions and cyclization processes. The presence of nitrogen atoms in its structure suggests potential for hydrogen bonding and coordination with metal ions, which can be relevant in medicinal chemistry and material science. This compound may exhibit pharmacological properties, making it of interest in drug discovery and development, particularly in targeting specific biological pathways. Its solubility, stability, and reactivity can vary based on environmental conditions and the presence of functional groups. Overall, this substance represents a class of heterocyclic compounds that are significant in various chemical and pharmaceutical applications.

Formula: C₁₇H₁₅N₉

InChI: InChI=1S/C17H15N9/c1-11(12-3-4-15-18-5-6-25(15)10-12)26-17-16(22-23-26)19-8-14(21-17)13-7-20-24(2)9-13/h3-11H,1-2H3/t11-/m0/s1

InChI key: InChIKey=XYDNMOZJKOGZLS-NSHDSACASA-N

SMILES: [C@@H](C)(N1C=2C(N=N1)=NC=C(N2)C3=CN(C)N=C3)C4=CN5C(C=C4)=NC=C5

Synonyms:

• Savolitinib
• AZD 6094
• 1-[(1S)-1-Imidazo[1,2-a]pyridin-6-ylethyl]-6-(1-methyl-1H-pyrazol-4-yl)-1H-1,2,3-triazolo[4,5-b]pyrazine
• 1H-1,2,3-Triazolo[4,5-b]pyrazine, 1-[(1S)-1-imidazo[1,2-a]pyridin-6-ylethyl]-6-(1-methyl-1H-pyrazol-4-yl)-
• HMPL 504

Volitinib

CAS: 1313725-88-0

Formula: C₁₇H₁₅N₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 345.3613

Ref: IN-DA009CK7

(S)-1-(1-(Imidazo[1,2-A]Pyridin-6-Yl)Ethyl)-6-(1-Methyl-1H-Pyrazol-4-Yl)-1H-[1,2,3]Triazolo[4,5-B]Pyrazine

CAS: 1313725-88-0

(S)-1-(1-(Imidazo[1,2-A]Pyridin-6-Yl)Ethyl)-6-(1-Methyl-1H-Pyrazol-4-Yl)-1H-[1,2,3]Triazolo[4,5-B]Pyrazine

Purity: 98%

Molecular weight: 345.36g/mol

Ref: 54-OR1023814

Savolitinib

CAS: 1313725-88-0

Savolitinib

Purity: ≥98%

Molecular weight: 345.36g/mol

Ref: 54-BUP04500

Savolitinib

CAS: 1313725-88-0

Savolitinib (Volitinib) (AZD-6094) is an effective, selective, and orally bioavailable c-Met inhibitor (IC50s: 5 nM/3 nM for c-Met/p-Met).

Formula: C₁₇H₁₅N₉

Purity: 98.12%

Color and Shape: Solid

Molecular weight: 345.36

Ref: TM-TQ0210

Savolitinib (AZD6094)

CAS: 1313725-88-0

Formula: C₁₇H₁₅N₉

Molecular weight: 345.37

Ref: 4Z-K-031053

Volitinib

CAS: 1313725-88-0

Inhibitor of c-Met kinase

Formula: C₁₇H₁₅N₉

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 345.36 g/mol

Ref: 3D-BV160378

Savolitinib

Controlled Product

CAS: 1313725-88-0

Applications Savolitinib is a potent and highly selective c-Met inhibitor. Savoltinib demonstrated anti-tumor efficacy in a panel of cMet-dysregulated gastric cancer PDX models. Savolitinib also demonstrated good antitmuor activities.
References Gavine, P., et al.: Mol. Oncol., 9, 323 (2015); Jia, H., et al.: J. Med. Chem., 57, 7577 (2014);

Formula: C₁₇H₁₅N₉

Color and Shape: Neat

Molecular weight: 345.36

Ref: TR-S142903