CAS 131543-23-2: Sildenafil Mesylate

Description: Sildenafil Mesylate is a pharmaceutical compound primarily known for its role as a treatment for erectile dysfunction and pulmonary arterial hypertension. It is a salt form of sildenafil, which is a selective inhibitor of phosphodiesterase type 5 (PDE5). This inhibition leads to increased levels of cyclic guanosine monophosphate (cGMP), resulting in vasodilation and improved blood flow. The mesylate salt enhances the solubility and bioavailability of sildenafil, making it more effective for therapeutic use. Sildenafil Mesylate is typically characterized by its white to off-white crystalline powder form, and it is soluble in water and organic solvents. The compound is often administered orally and is known for its relatively rapid onset of action. Its pharmacokinetics involve absorption, distribution, metabolism primarily in the liver, and excretion through urine. As with any medication, it is essential to consider potential side effects, contraindications, and interactions with other drugs when prescribing or using Sildenafil Mesylate.

Formula: C₂₈H₃₀N₂O₆S

InChI: InChI=1/C27H26N2O3.CH4O3S/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28;1-5(2,3)4/h2-11,20H,12-17H2,1H3;1H3,(H,2,3,4)/t20-;/m1./s1

Synonyms:

• Win 55,212-2 Mesylate
• (R)-(+)-[2,3-Dihydro-5-Methyl-3-(4-Morpholinylmethyl)Pyrrolo[1,2,3-De]-1,4-Benzoxazin-6-Yl]-1-Naphthalenylmethanone Mesylate
• R(+)-[2,3-Dihydro-5-Methyl-3-[(Morpholinyl)Methyl]Pyrrolo[1,2,3-De]-1,4-Benzoxazinyl]-(1-Naphthalenyl)Methanone Mesylate
• R(+)-Win 55,212-2 Mesylate
• R(+)-Win 55,212-2 ,Mesylate High Affinit Y Cannabi
• (R)-(+)-(2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1.2.3-de]-1,4-benzoxazin-6-yl)-1-naphthalenylmethanonemesy
• 212-2Mesylate
• [(3R)-5-methyl-3-(morpholin-4-ylmethyl)-2,3-dihydro[1,4]oxazino[2,3,4-hi]indol-6-yl](naphthalen-1-yl)methanone methanesulfonate

Methanone, [(3R)-2,3-dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenyl-, methanesulfonate (1:1)

CAS: 131543-23-2

• Formula: C₂₈H₃₀N₂O₆S
• Purity: 98%
• Molecular weight: 522.6126

WIN 55,212-2 Mesylate

CAS: 131543-23-2

WIN 55,212-2 Mesylate ((R)-(+)-WIN 55212) is a potent aminoalkylindole cannabinoid (CB) receptor agonist with Kis …

• Formula: C₂₈H₃₀N₂O₆S
• Purity: 98% - 99.71%
• Color and Shape: White To Off-White Solid
• Molecular weight: 522.61

Win 55,212-2 mesylate

CAS: 131543-23-2

Cannabinoid (CB) receptor agonist. Anti-hyperalgesic effects demonstrated in a rat model of neuropathic pain. Has …

• Formula: C₂₇H₂₆N₂O₃·CH₃SO₃H
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 522.61 g/mol

[(3R)-2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenyl-methanone Monomethanesulfonate

CAS: 131543-23-2

• Formula: C₂₇H₂₆N₂O₃·CH₄SO₃
• Color and Shape: Off-White
• Molecular weight: 522.60