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CAS 131543-23-2

:

Sildenafil Mesylate

Description:
Sildenafil Mesylate is a pharmaceutical compound primarily known for its role as a treatment for erectile dysfunction and pulmonary arterial hypertension. It is a salt form of sildenafil, which is a selective inhibitor of phosphodiesterase type 5 (PDE5). This inhibition leads to increased levels of cyclic guanosine monophosphate (cGMP), resulting in vasodilation and improved blood flow. The mesylate salt enhances the solubility and bioavailability of sildenafil, making it more effective for therapeutic use. Sildenafil Mesylate is typically characterized by its white to off-white crystalline powder form, and it is soluble in water and organic solvents. The compound is often administered orally and is known for its relatively rapid onset of action. Its pharmacokinetics involve absorption, distribution, metabolism primarily in the liver, and excretion through urine. As with any medication, it is essential to consider potential side effects, contraindications, and interactions with other drugs when prescribing or using Sildenafil Mesylate.
Formula:C28H30N2O6S
InChI:InChI=1/C27H26N2O3.CH4O3S/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28;1-5(2,3)4/h2-11,20H,12-17H2,1H3;1H3,(H,2,3,4)/t20-;/m1./s1
SMILES:Cc1c(c2cccc3c2n1[C@H](CN1CCOCC1)CO3)C(=O)c1cccc2ccccc12.CS(=O)(=O)O
Synonyms:
  • Win 55,212-2 Mesylate
  • (R)-(+)-[2,3-Dihydro-5-Methyl-3-(4-Morpholinylmethyl)Pyrrolo[1,2,3-De]-1,4-Benzoxazin-6-Yl]-1-Naphthalenylmethanone Mesylate
  • R(+)-[2,3-Dihydro-5-Methyl-3-[(Morpholinyl)Methyl]Pyrrolo[1,2,3-De]-1,4-Benzoxazinyl]-(1-Naphthalenyl)Methanone Mesylate
  • R(+)-Win 55,212-2 Mesylate
  • R(+)-Win 55,212-2 ,Mesylate High Affinit Y Cannabi
  • (R)-(+)-(2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1.2.3-de]-1,4-benzoxazin-6-yl)-1-naphthalenylmethanonemesy
  • 212-2Mesylate
  • [(3R)-5-methyl-3-(morpholin-4-ylmethyl)-2,3-dihydro[1,4]oxazino[2,3,4-hi]indol-6-yl](naphthalen-1-yl)methanone methanesulfonate
  • WIN 55,212-2
  • [(3R)-2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenyl-methanone Monomethanesulfonate
  • See more synonyms
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Found 3 products.
  • WIN 55,212-2 Mesylate
    Targetmol
    + Info

    WIN 55,212-2 Mesylate

    CAS:
    WIN 55,212-2 Mesylate ((R)-(+)-WIN 55212) is a potent aminoalkylindole cannabinoid (CB) receptor agonist with Kis of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively. Cannabinoid analogue WIN 55,212-2 Mesylate exhibited a novel anticancer effect against human tumors.
    Formula:C28H30N2O6S
    Purity:98% - 99.71%
    Color and Shape:Solid
    Molecular weight:522.61

    Ref: TM-T4458

    1mL*10mM (DMSO)
    103.00€
  • Win 55,212-2 mesylate
    Biosynth
    + Info

    Win 55,212-2 mesylate

    Controlled Product
    CAS:
    Cannabinoid (CB) receptor agonist. Anti-hyperalgesic effects demonstrated in a rat model of neuropathic pain. Has anti-inflammatory properties, mediated by activation of peroxisome proliferator-activated receptors (PPARα) transcriptional activity. Inhibits LPS-induced chronic neuroinflammation, by blocking activation of microglial cells.
    Formula:C27H26N2O3·CH3SO3H
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:522.61 g/mol

    Ref: 3D-FW65206

    25mg
    269.00€
    50mg
    463.00€
    100mg
    710.00€
  • [(3R)-2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphtha…
    TRC
    + Info

    [(3R)-2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenyl-methanone Monomethanesulfonate

    Controlled Product
    CAS:
    Formula:C27H26N2O3·CH4SO3
    Color and Shape:Neat
    Molecular weight:522.60

    Ref: TR-D451850

    500mg
    14,624.00€