CAS 13171-25-0

Trimetazidine dihydrochloride

Description:

Trimetazidine dihydrochloride is a pharmaceutical compound primarily used as an antianginal agent, particularly in the management of stable angina pectoris. It functions by optimizing cellular metabolism, enhancing glucose utilization, and improving energy production in ischemic heart tissues. The substance is characterized by its chemical formula, which includes two hydrochloride ions, indicating its salt form. Trimetazidine is known for its ability to reduce the frequency and severity of angina attacks without affecting heart rate or blood pressure significantly. It is typically administered orally and is well-absorbed in the gastrointestinal tract. The compound exhibits a favorable safety profile, with side effects generally being mild and transient. Trimetazidine dihydrochloride is often prescribed in conjunction with other antianginal medications to provide a comprehensive approach to angina management. Its mechanism of action, primarily involving the modulation of fatty acid oxidation and promotion of glucose oxidation, makes it a unique therapeutic option in cardiovascular medicine.

Formula:C₁₄H₂₂N₂O₃·2ClH

InChI:InChI=1S/C14H22N2O3.2ClH/c1-17-12-5-4-11(13(18-2)14(12)19-3)10-16-8-6-15-7-9-16;;/h4-5,15H,6-10H2,1-3H3;2*1H

InChI key:InChIKey=VYFLPFGUVGMBEP-UHFFFAOYSA-N

SMILES:C(C1=C(OC)C(OC)=C(OC)C=C1)N2CCNCC2.Cl

Synonyms:

1-(2,3,4-Trimethoxybenzyl)Piperazine
1-(2,3,4-Trimethoxybenzyl)Piperazine Dihydrochloride
1-(2,3,4-Trimethoxybenzyl)Piperazinediium
1-[(2,3,4-Trimethoxyphenyl)Methyl]Piperazine Dihydrochloride
Kyurinett
Piperazine, 1-(2,3,4-trimethoxybenzyl)-, dihydrochloride
Piperazine, 1-[(2,3,4-trimethoxyphenyl)methyl]-, dihydrochloride
Piperazine, 1-[(2,3,4-trimethoxyphenyl)methyl]-, hydrochloride (1:2)
S 4004
Trimetazidine 2HCl
Trimetazidine Dihydrochloride
Trivedon
Vastarel
Vastarel F
See more synonyms

Purity (%)

100

Found 11 products.

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Trimetazidine Dihydrochloride
CAS:
- 13171-25-0
Formula:C₁₄H₂₂N₂O₃·2HCl
Purity:>98.0%(HPLC)(N)
Color and Shape:White to Almost white powder to crystal
Molecular weight:339.26
Ref: 3B-T2726
5g
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Trimetazidine Dihydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 13171-25-0
Color and Shape:Neat
Ref: 61-FOR0539.00
10mg
306.00€
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Trimetazidine Dihydrochloride 1.0 mg/ml in Methanol (as free base)
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 13171-25-0
Color and Shape:Single Solution
Ref: 61-AMP0539.00-01
1ml
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TRIMETAZIDINE FOR SYSTEM SUITABILITY CRS
CAS:
- 13171-25-0
TRIMETAZIDINE FOR SYSTEM SUITABILITY CRS
Formula:C₁₄H₂₄Cl₂N₂O₃
Color and Shape:Removed
Molecular weight:339.258
Ref: 41-Y0000093
50mg
115.00€
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Trimetazidine dihydrochloride
CAS:
- 13171-25-0
Trimetazidine, an anti-ischemic agent, enhances myocardial glucose use, inhibits fat metabolism, and helps with angina.
Formula:C₁₄H₂₄Cl₂N₂O₃
Purity:99.58%
Color and Shape:Crystalline Solid
Molecular weight:339.258
Ref: TM-T0988
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Trimetazidine DiHCl
CAS:
- 13171-25-0
Formula:C₁₄H₂₂N₂O₃·2HCl
Color and Shape:White To Off-White Solid
Molecular weight:266.34 2*36.46
Ref: 4Z-T-352
5mg
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10mg
349.00€
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25mg
444.00€
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50mg
635.00€
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100mg
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Trimetazidine Dihydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 13171-25-0
Color and Shape:Neat
Ref: 86-MM0539.00
250mg
1,785.00€
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Trimetazidine dihydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 13171-25-0
Formula:C₁₄H₂₂N₂O₃ClH
Color and Shape:Neat
Molecular weight:339.26
Ref: 04-C17873000
100mg
65.00€
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Trimetazidine Dihydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 13171-25-0
Applications Coronary vasodilator. Antianginal. References Fujita, et al.: Jpn. J. Pharmacol., 17, 19 (1967), Harpey, C., et al.: Cardiovasc. Drug Rev., 6, 292 (1989), 
Formula:C₁₄H₂₂N₂O₃·2ClH
Color and Shape:Off White
Molecular weight:339.26
Ref: TR-T795610
1g
573.00€
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5mg
188.00€
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100mg
345.00€
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Trimetazidine dihydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 13171-25-0
Trimetazidine dihydrochloride is a drug that has been shown to have statistically significant effects on mitochondrial functions. Trimetazidine is an anti-ischemic agent, which prevents myocardial infarcts by inhibiting the release of natriuretic peptides and thus reducing the level of intracellular cGMP. Trimetazidine dihydrochloride has also been shown to reduce cardiac hypertrophy and fibrosis, which are caused by oxidative stress and hypertension.
Formula:C₁₄H₂₂N₂O₃•(HCl)₂
Purity:Min. 95%
Color and Shape:Powder
Molecular weight:339.26 g/mol
Ref: 3D-FT28515
10g
182.00€
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Piperazine, 1-[(2,3,4-trimethoxyphenyl)methyl]-, hydrochloride (1:2)
CAS:
- 13171-25-0
Formula:C₁₄H₂₄Cl₂N₂O₃
Color and Shape:Solid
Molecular weight:339.2580
Ref: IN-DA000ZM9
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