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CAS 13171-25-0

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Trimetazidine dihydrochloride

Description:
Trimetazidine dihydrochloride is a pharmaceutical compound primarily used as an antianginal agent, particularly in the management of stable angina pectoris. It functions by optimizing cellular metabolism, enhancing glucose utilization, and improving energy production in ischemic heart tissues. The substance is characterized by its chemical formula, which includes two hydrochloride ions, indicating its salt form. Trimetazidine is known for its ability to reduce the frequency and severity of angina attacks without affecting heart rate or blood pressure significantly. It is typically administered orally and is well-absorbed in the gastrointestinal tract. The compound exhibits a favorable safety profile, with side effects generally being mild and transient. Trimetazidine dihydrochloride is often prescribed in conjunction with other antianginal medications to provide a comprehensive approach to angina management. Its mechanism of action, primarily involving the modulation of fatty acid oxidation and promotion of glucose oxidation, makes it a unique therapeutic option in cardiovascular medicine.
Formula:C14H22N2O3·2ClH
InChI:InChI=1S/C14H22N2O3.2ClH/c1-17-12-5-4-11(13(18-2)14(12)19-3)10-16-8-6-15-7-9-16;;/h4-5,15H,6-10H2,1-3H3;2*1H
InChI key:InChIKey=VYFLPFGUVGMBEP-UHFFFAOYSA-N
SMILES:C(C1=C(OC)C(OC)=C(OC)C=C1)N2CCNCC2.Cl
Synonyms:
  • 1-(2,3,4-Trimethoxybenzyl)Piperazine
  • 1-(2,3,4-Trimethoxybenzyl)Piperazine Dihydrochloride
  • 1-(2,3,4-Trimethoxybenzyl)Piperazinediium
  • 1-[(2,3,4-Trimethoxyphenyl)Methyl]Piperazine Dihydrochloride
  • Kyurinett
  • Piperazine, 1-(2,3,4-trimethoxybenzyl)-, dihydrochloride
  • Piperazine, 1-[(2,3,4-trimethoxyphenyl)methyl]-, dihydrochloride
  • Piperazine, 1-[(2,3,4-trimethoxyphenyl)methyl]-, hydrochloride (1:2)
  • S 4004
  • Trimetazidine 2HCl
  • See more synonyms
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