CAS 132388-68-2: N(alpha)-boc-N(gamma)-trityl-L-aspara-gine
Description:N(alpha)-Boc-N(gamma)-trityl-L-asparagine is a protected derivative of the amino acid L-asparagine, commonly used in peptide synthesis and organic chemistry. The "Boc" (tert-butyloxycarbonyl) group serves as a protective group for the amino functionality at the alpha position, while the "trityl" group protects the side chain amine at the gamma position. This compound is characterized by its stability under acidic conditions, making it suitable for various synthetic applications. It is typically a white to off-white solid and is soluble in organic solvents such as dichloromethane and dimethylformamide, but less soluble in water. The presence of both Boc and trityl groups allows for selective deprotection, facilitating the synthesis of complex peptides. Additionally, this compound is often utilized in the development of pharmaceuticals and bioconjugates due to its ability to form stable linkages and its compatibility with various coupling reagents. Proper handling and storage are essential, as with many chemical substances, to maintain its integrity and reactivity.
Formula:C28H30N2O5
InChI:InChI=1/C28H30N2O5/c1-27(2,3)35-26(34)29-23(25(32)33)19-24(31)30-28(20-13-7-4-8-14-20,21-15-9-5-10-16-21)22-17-11-6-12-18-22/h4-18,23H,19H2,1-3H3,(H,29,34)(H,30,31)(H,32,33)/t23-/m0/s1
- Synonyms:
- Boc-N-beta-Trityl-L-Asparagine
- Boc-Asn(Trt)-OH
- N2-(tert-butoxycarbonyl)-N-trityl-L-asparagine
- N-Boc-N'-trityl-L-asparagine
![L-Asparagine, N2-[(1,1-dimethylethoxy)carbonyl]-N-(triphenylmethyl)-](https://static.cymitquimica.com/products/IN/thumb/DA0010ML.jpg)
