CAS 132388-68-2

N(alpha)-boc-N(gamma)-trityl-L-aspara-gine

Description:

N(alpha)-Boc-N(gamma)-trityl-L-asparagine is a protected derivative of the amino acid L-asparagine, commonly used in peptide synthesis and organic chemistry. The "Boc" (tert-butyloxycarbonyl) group serves as a protective group for the amino functionality at the alpha position, while the "trityl" group protects the side chain amine at the gamma position. This compound is characterized by its stability under acidic conditions, making it suitable for various synthetic applications. It is typically a white to off-white solid and is soluble in organic solvents such as dichloromethane and dimethylformamide, but less soluble in water. The presence of both Boc and trityl groups allows for selective deprotection, facilitating the synthesis of complex peptides. Additionally, this compound is often utilized in the development of pharmaceuticals and bioconjugates due to its ability to form stable linkages and its compatibility with various coupling reagents. Proper handling and storage are essential, as with many chemical substances, to maintain its integrity and reactivity.

Formula: C₂₈H₃₀N₂O₅

InChI: InChI=1/C28H30N2O5/c1-27(2,3)35-26(34)29-23(25(32)33)19-24(31)30-28(20-13-7-4-8-14-20,21-15-9-5-10-16-21)22-17-11-6-12-18-22/h4-18,23H,19H2,1-3H3,(H,29,34)(H,30,31)(H,32,33)/t23-/m0/s1

SMILES: CC(C)(C)OC(=N[C@@H](CC(=NC(c1ccccc1)(c1ccccc1)c1ccccc1)O)C(=O)O)O

Synonyms:

• Boc-N-beta-Trityl-L-Asparagine
• Boc-Asn(Trt)-OH
• N2-(tert-butoxycarbonyl)-N-trityl-L-asparagine
• N-Boc-N'-trityl-L-asparagine

Nα-tert-Butoxycarbonyl-Nγ-trityl-L-asparagine

CAS: 132388-68-2

Formula: C₂₈H₃₀N₂O₅

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 474.56

Ref: 3B-B3789

Nα-Boc-Nγ-trityl-L-asparagine, 98%

CAS: 132388-68-2

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₈H₃₀N₂O₅

Purity: 98%

Molecular weight: 474.56

Ref: 02-H62446

L-Asparagine, N2-[(1,1-dimethylethoxy)carbonyl]-N-(triphenylmethyl)-

CAS: 132388-68-2

Formula: C₂₈H₃₀N₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 474.5482

Ref: IN-DA0010ML

Boc-Asn(Trt)-OH

CAS: 132388-68-2

Boc-Asn(Trt)-OH

Formula: C₂₈H₃₀N₂O₅

Purity: >98%

Molecular weight: 474.55

Ref: 54-OR1012478

Boc-Asn(Trt)-OH

CAS: 132388-68-2

Boc-Asn(Trt)-OH

Formula: C₂₈H₃₀N₂O₅

Purity: 98%

Molecular weight: 474.55

Ref: IN-DG213070

Boc-Asn(Trt)-OH

CAS: 132388-68-2

Formula: C₂₈H₃₀N₂O₅

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 474.55

Ref: 7W-GM9595

N-a-t-Boc-N-g-trityl-L-asparagine

CAS: 132388-68-2

N-a-t-Boc-N-g-trityl-L-asparagine is a recombinant human protein that has been synthesized in E. coli. It is a peptide with 17β-estradiol at its C terminus, and it binds to the oestrogen receptor α (ERα) via hydrogen bonding interactions. The linker between the asparagine and estradiol is a Boc group that can be removed by protease activity, revealing the active form of 17β-estradiol. ERα ligates to N-a-t-Boc-N-g-trityl L asparagine with high affinity, and this interaction is reversible. The linker also contains a functional group for surface attachment, which may be used to attach this peptide to a solid support or tissue culture substrate for use in cell cultures.
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Formula: C₂₈H₃₀N₂O₅

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 474.55 g/mol

Ref: 3D-FB39381

Boc-Asn(Trt)-OH

CAS: 132388-68-2

M03265 - Boc-Asn(Trt)-OH

Formula: C₂₈H₃₀N₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 474.215

Ref: 10-M03265