CAS 1328987-85-4

Formula: C27H20F2N2O7S2

InChI: InChI=1S/C27H20F2N2O7S2/c28-17-5-12-22(21(29)13-17)38-24(15-3-8-19(9-4-15)40(35,36)20-10-11-20)25(32)31-27-30-14-23(39-27)37-18-6-1-16(2-7-18)26(33)34/h1-9,12-14,20,24H,10-11H2,(H,33,34)(H,30,31,32)/t24-/m1/s1

InChI key: XJFUEUNGZVAEIX-XMMPIXPASA-N

SMILES: C1CC1S(=O)(=O)C2=CC=C(C=C2)[C@H](C(=O)NC3=NC=C(S3)OC4=CC=C(C=C4)C(=O)O)OC5=C(C=C(C=C5)F)F

Glucokinase activator 1

CAS: 1328987-85-4

Glucokinase activator 1 (GKA1) is a protein that activates glucokinase, which is an enzyme that promotes the phosphorylation of glucose to glucose-6-phosphate. GKA1 has been shown to activate glucokinase in a mutant strain of E. coli, which has been shown to have increased lipoprotein lipase activity and enhanced uptake of glucose. This protein is also able to stimulate the production of insulin by increasing transcriptional regulation and messenger RNA levels. GKA1 may be used as a potential therapy for diabetes and as a diagnostic tool for measuring insulin resistance.

Formula: C₂₇H₂₀F₂N₂O₇S₂

Purity: Min. 95%

Molecular weight: 586.6 g/mol

Ref: 3D-DDC98785

Glucokinase activator 1

CAS: 1328987-85-4

Glucokinase activator 1 is a liver-directed glucokinase activator (EC50: 34 nM).

Formula: C₂₇H₂₀F₂N₂O₇S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 586.58

Ref: TM-T11418