CAS 132907-72-3
:Ramosetron Hydrochloride
Description:
Ramosetron Hydrochloride is a selective serotonin 5-HT3 receptor antagonist primarily used in the management of nausea and vomiting, particularly in patients undergoing chemotherapy or surgery. It is characterized by its ability to block the action of serotonin at these receptors, which play a crucial role in the vomiting reflex. The compound is typically administered orally or intravenously, depending on the clinical scenario. Ramosetron is known for its relatively long half-life, allowing for less frequent dosing compared to some other antiemetics. Its chemical structure includes a piperidine ring, contributing to its pharmacological properties. The hydrochloride salt form enhances its solubility and stability, making it suitable for pharmaceutical formulations. Common side effects may include headache, constipation, and dizziness, although it is generally well-tolerated. As with any medication, its use should be guided by a healthcare professional, considering potential interactions and contraindications. Overall, Ramosetron Hydrochloride represents an important option in the therapeutic arsenal against nausea and vomiting.
Formula:C17H18ClN3O
InChI:InChI=1/C17H17N3O.ClH/c1-20-9-13(12-4-2-3-5-16(12)20)17(21)11-6-7-14-15(8-11)19-10-18-14;/h2-5,9-11H,6-8H2,1H3,(H,18,19);1H/t11-;/m1./s1
InChI key:InChIKey=XIXYTCLDXQRHJO-RFVHGSKJSA-N
SMILES:C(=O)(C=1C=2C(N(C)C1)=CC=CC2)[C@H]3CC4=C(CC3)N=CN4.Cl
Synonyms:- (-)-(R)-5-[(1-Methyl-1H-indol-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H-benzimidazole monohydrochloride
- (1-methyl-1H-indol-3-yl)[(6R)-4,5,6,7-tetrahydro-1H-benzimidazol-6-yl]methanone hydrochloride (1:1)
- (R)-(-)-Ramosetron hydrochloride
- Irribow
- Methanone, (1-methyl-1H-indol-3-yl)(4,5,6,7-tetrahydro-1H-benzimidazol-5-yl)-, monohydrochloride, (R)-
- Methanone, (1-methyl-1H-indol-3-yl)[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol-5-yl]-, monohydrochloride
- Methanone, (1-methyl-1H-indol-3-yl)[(6R)-4,5,6,7-tetrahydro-1H-benzimidazol-6-yl]-, hydrochloride (1:1)
- Ramosetron HCl
- Ym 060
- Ramosetron hydrochloride
- Nasea OD
- (r)-monohydrochlorid
- (r)-5-((1-methyl-3-indolyl)carbonyl)-4,5,6,7-tetrahydro-1h-benzimidazolehydr
- RAMOSETRON HYDROCHLORIDE 98.5% MIN
- ym060
- (R)-YM-060
- (1-methyl-1h-indol-3-yl)(4,5,6,7-tetrahydro-1h-benzimidazol-5-yl)-methanon
- Ramosetron Hydrochlorid
- (-)-5-(R)-[(1-methylindole-3-yl)carbonyl]-4,5,6,7-tetrahydrobenzimidazole hydrochloride
- (1-methylindol-3-yl)-[(5r)-4,5,6,7-tetrahydro-3h-benzimidazol-5-yl]methanone hydrochloride
- See more synonyms
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Found 6 products.
Methanone, (1-methyl-1H-indol-3-yl)[(6R)-4,5,6,7-tetrahydro-1H-benzimidazol-6-yl]-, hydrochloride (1:1)
CAS:Formula:C17H18ClN3OPurity:98%Color and Shape:SolidMolecular weight:315.7973Ramosetron hydrochloride
CAS:Ramosetron hydrochloride (YM-060) is a serotonin 5-HT3 receptor antagonist. It is used to treat diarrhea-predominant irritable bowel syndrome and nausea.Formula:C17H18ClN3OPurity:99.95%Color and Shape:White SolidMolecular weight:315.8Ramosetron Hydrochloride
CAS:Controlled ProductStability Hygroscopic
Applications Selective serotonin 5HT3, receptor antagonist; structurally different from Ondansetron (O655000), Granisetron (G780000). Antiemetic.
References Miyata, K., et al.: J. Pharmacol. Exp. Ther., 259, 15 (1991), Miura, H., et al.: Biomed. Chromatogr., 8, 103 (1994), Tabata, H., et al.: Arzneim.-Forsch., 45, 760 (1995),Formula:C17H17N3O·ClHColor and Shape:NeatMolecular weight:315.8Ramosetron hydrochloride
CAS:Controlled Product5-HT3 serotonin receptor antagonistFormula:C17H17N3O•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:315.8 g/molRef: 3D-FR27680
Discontinued product
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